Patents by Inventor Barry E. Leonard
Barry E. Leonard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230288428Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: April 26, 2023Publication date: September 14, 2023Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Patent number: 11668716Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: GrantFiled: August 12, 2021Date of Patent: June 6, 2023Assignee: BECTON, DICKINSON AND COMPANYInventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Publication number: 20210373029Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: August 12, 2021Publication date: December 2, 2021Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Patent number: 11119107Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: GrantFiled: February 19, 2020Date of Patent: September 14, 2021Assignee: BECTON, DICKINSON AND COMPANYInventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Publication number: 20200200761Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: February 19, 2020Publication date: June 25, 2020Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Patent number: 10605813Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: GrantFiled: January 24, 2019Date of Patent: March 31, 2020Assignee: BECTON, DICKINSON AND COMPANYInventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Publication number: 20190170757Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: January 24, 2019Publication date: June 6, 2019Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Patent number: 10228375Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: GrantFiled: June 21, 2017Date of Patent: March 12, 2019Assignee: Becton, Dickinson and CompanyInventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Publication number: 20170285039Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: June 21, 2017Publication date: October 5, 2017Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Patent number: 9719998Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: GrantFiled: March 2, 2016Date of Patent: August 1, 2017Assignee: Becton Dickinson and CompanyInventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord
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Publication number: 20160266131Abstract: Water soluble light harvesting multichromophores that have an ultraviolet absorption maximum are provided. In some embodiments, the multichromophores include a conjugated segment including a fused 6-5-6 tricyclic co-monomer and a UV absorbance-modifying co-monomer. The multichromophores may include an acceptor chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. In some embodiments, a specific binding member is covalently linked to the multichromophore. Also provided are methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule using compositions including the light harvesting multichromophores. Kits and systems for practicing the subject methods are also provided.Type: ApplicationFiled: March 2, 2016Publication date: September 15, 2016Inventors: Yongchao Liang, Frank P. Uckert, Glenn P. Bartholomew, Barry E. Leonard, Brent S. Gaylord