Patents by Inventor Barry E. Rothenberg

Barry E. Rothenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11884910
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: August 3, 2023
    Date of Patent: January 30, 2024
    Assignee: Embrient, Inc.
    Inventors: Kyong-su Son, Royal Q. Le, Barry E. Rothenberg
  • Publication number: 20230374437
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: August 3, 2023
    Publication date: November 23, 2023
    Applicant: Embrient, Inc.
    Inventors: Kyong-su Son, Royal Q. Le, Barry E. Rothenberg
  • Patent number: 11780871
    Abstract: Compositions and methods are presented that reduce the risk for ARDS and/or need for ventilation in a patient diagnosed with a coronavirus, and particularly SARS-CoV-2 virus, a SARS virus, or a MERS virus. In preferred aspects, HMW-HA is administered to the lung before onset of ARDS and/or cytokine storm. Additionally, NAD+ may be co-administered or prophylactically administered where NAD+levels are low.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: October 10, 2023
    Assignee: BILLUPS-ROTHENBERG, INC.
    Inventor: Barry E. Rothenberg
  • Publication number: 20230242861
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: March 28, 2023
    Publication date: August 3, 2023
    Applicant: Embrient, Inc.
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Patent number: 11634681
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: April 25, 2023
    Assignee: EMBRIENT, INC.
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Patent number: 11591562
    Abstract: Provided herein are systems for continuously measuring oxygen and carbon dioxide gas levels inside a cell culture incubator, comprising an oxygen sensor that uses LED based fluorescence technology to determine the amount of oxygen in the surrounding atmosphere, a carbon dioxide sensor that uses LED based Non-dispersive Infra-Red (NDIR) technology to determine the amount of carbon dioxide in the surrounding atmosphere, and electronics to wirelessly monitor the output from the oxygen sensor and carbon dioxide sensor. Most preferably, the system can be placed inside a cell culture incubator, and sensor readings are pre-compensated for temperature, pressure, and humidity. Also provided herein are methods of using the same.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: February 28, 2023
    Assignee: BILLUPS-ROTHENBERG, INC.
    Inventors: Royal Q. Le, Kyong Son, Barry E. Rothenberg
  • Patent number: 11471840
    Abstract: Provided herein are gas mixing systems, comprising a gas inlet for receiving two or more gases and a mixing chamber with a static mixer for mixing the gases. Preferred mixing chambers further comprise a reduced pressure compartment downstream of the static mixer that is in fluid communication with the gas inlet. A gas outlet is in fluid communication with the mixing chamber, and one or more sensors are coupled to the reduced pressure compartment and are configured to continuously sense various parameters such as barometric pressure and the percentage of oxygen in the gas mixture moving through the mixing device. Most typically, the readings of the sensor are pre-compensated for temperature, pressure, and humidity. Also provided herein are methods for using the same.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: October 18, 2022
    Assignee: BILLUPS-ROTHENBERG, INC.
    Inventors: Royal Q. Le, Kyong Son, Barry E. Rothenberg
  • Publication number: 20220275322
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: May 16, 2022
    Publication date: September 1, 2022
    Applicant: Embrient, Inc.
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Patent number: 11365385
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: June 21, 2022
    Assignee: EMBRIENT, INC.
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Publication number: 20220089998
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: November 10, 2021
    Publication date: March 24, 2022
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Patent number: 11203737
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: December 21, 2021
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-Su Son
  • Publication number: 20210324322
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: June 24, 2021
    Publication date: October 21, 2021
    Inventors: Royal Q. Le, Barry E. Rothenberg, Kyong-su Son
  • Patent number: 11072773
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: July 27, 2021
    Inventors: Barry E. Rothenberg, Kyong-su Son, Royal Q Le
  • Publication number: 20210079336
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Inventors: Barry E. Rothenberg, Kyong-su Son, Royal Q. Le
  • Patent number: 10900010
    Abstract: An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: January 26, 2021
    Inventors: Barry E. Rothenberg, Kyong-su Son, Royal Q Le
  • Publication number: 20200190459
    Abstract: Provided herein are systems for continuously measuring oxygen and carbon dioxide gas levels inside a cell culture incubator, comprising an oxygen sensor that uses LED based fluorescence technology to determine the amount of oxygen in the surrounding atmosphere, a carbon dioxide sensor that uses LED based Non-dispersive Infra-Red (NDIR) technology to determine the amount of carbon dioxide in the surrounding atmosphere, and electronics to wirelessly monitor the output from the oxygen sensor and carbon dioxide sensor. Most preferably, the system can be placed inside a cell culture incubator, and sensor readings are pre-compensated for temperature, pressure, and humidity. Also provided herein are methods of using the same.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 18, 2020
    Inventors: Royal Q. Le, Kyong Son, Barry E. Rothenberg
  • Publication number: 20200188865
    Abstract: Provided herein are gas mixing systems, comprising a gas inlet for receiving two or more gases and a mixing chamber with a static mixer for mixing the gases. Preferred mixing chambers further comprise a reduced pressure compartment downstream of the static mixer that is in fluid communication with the gas inlet. A gas outlet is in fluid communication with the mixing chamber, and one or more sensors are coupled to the reduced pressure compartment and are configured to continuously sense various parameters such as barometric pressure and the percentage of oxygen in the gas mixture moving through the mixing device. Most typically, the readings of the sensor are pre-compensated for temperature, pressure, and humidity. Also provided herein are methods for using the same.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 18, 2020
    Inventors: Royal Q. Le, Kyong Son, Barry E. Rothenberg
  • Patent number: 10138455
    Abstract: A incubator chamber comprises a base, lid and plurality of trays, each of which are stackable upon one another in an open or closed configuration. A clamp could be provided having an interior cavity sized and dimensioned to simultaneously receive a portion of a perimeter of each of a base and a lid.
    Type: Grant
    Filed: March 15, 2016
    Date of Patent: November 27, 2018
    Inventor: Barry E. Rothenberg
  • Publication number: 20160194596
    Abstract: A incubator chamber comprises a base, lid and plurality of trays, each of which are stackable upon one another in an open or closed configuration. A clamp could be provided having an interior cavity sized and dimensioned to simultaneously receive a portion of a perimeter of each of a base and a lid.
    Type: Application
    Filed: March 15, 2016
    Publication date: July 7, 2016
    Inventor: Barry E. Rothenberg
  • Patent number: 9315769
    Abstract: A incubator chamber comprises a base, lid and plurality of trays, each of which are stackable upon one another in an open or closed configuration. A clamp could be provided having an interior cavity sized and dimensioned to simultaneously receive a portion of a perimeter of each of a base and a lid.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: April 19, 2016
    Assignee: Billups-Rothenberg, Inc.
    Inventor: Barry E. Rothenberg