Abstract: Methods, non-transitory computer readable media, session director apparatuses, and network traffic management systems that facilitate packet data network (PDN) service slicing with microsegmentation in an evolved packet core are disclosed. With this technology, a create session request (CSR) general packet radio service (GPRS) tunneling protocol (GTP) control (GTP-c) message is intercepted. A lookup key is then determined based on content of the intercepted CSR GTP-c message. A PDN gateway (PGW) identifier for a PGW is obtained using a slice name obtained using the lookup key. The intercepted CSR GTP-c message is modified to include the obtained PGW identifier. Subsequently, the modified CSR GTP-c message is steered based on the obtained PGW identifier, such as directly to the PGW or to a serving gateway (SGW) module associated with the PGW.