Patents by Inventor Barry I. Gold

Barry I. Gold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds and methods for inhibition of AP endonuclease-1/redox factor-1 (HAPE1) activity
    Patent number: 9624235
    Abstract: A method for treating a neoplasm in a subject, comprising co-administering to the subject a therapeutically effective amount of an anticancer agent and a substituted 6,7-methylenedioxy-4-amino-quinoline, or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: April 18, 2017
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Barry I. Gold, Xiangqun Xie, Ajay Srinivasan, LiRong Wang
  • COMPOUNDS AND METHODS FOR INHIBITION OF AP ENDONUCLEASE-1/REDOX FACTOR-1 (HAPE1) ACTIVITY
    Publication number: 20140371259
    Abstract: A method for treating a neoplasm in a subject, comprising co-administering to the subject a therapeutically effective amount of an anticancer agent and a substituted 6,7-methylenedioxy-4-amino-quinoline, or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: January 29, 2013
    Publication date: December 18, 2014
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Barry I. Gold, Xiangqun Xie, Ajay Srinivasan, LiRong Wang
  • Halogenated aminoquinolines and oligonucleotides containing the same
    Patent number: 7449571
    Abstract: Novel synthetic monomers that have the capacity to be assembled into defined oligomers which bind with sequence specificity to duplex Watson-Crick DNA via a triple helix motif are provided.
    Type: Grant
    Filed: June 14, 2005
    Date of Patent: November 11, 2008
    Assignee: Board of Regents of the University of Nebraska
    Inventor: Barry I. Gold
  • Synthetic triple helix-forming compound precursors
    Patent number: 5844110
    Abstract: The present invention discloses novel monomeric compositions which are substituted quinoline- or quinazoline-based structures capable of hydrogen bonding specifically with interstrand purine-pyrimidine base pairs in a double-stranded Watson-Crick DNA molecule. Furthermore, the novel monomeric compounds of the present invention are capable of being assembled in specific sequences into oligomers capable of binding with sequence specificity to duplex DNA via a triple helix motif.
    Type: Grant
    Filed: February 1, 1995
    Date of Patent: December 1, 1998
    Assignee: University of Nebraska Board of Regents
    Inventor: Barry I. Gold