Patents by Inventor Barry James Connell

Barry James Connell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Animal stroke model
    Patent number: 9086405
    Abstract: An animal stroke model is provided. The model is useful in the study of brain ischemia and/or reperfusion injury and in identification and testing of compounds and interventions useful in the treatment of stroke. The method is carried out in a non-human mammal, such as rat. The method of inducing ischemia and/or reperfusion injury involves exposing a portion of the middle cerebral artery (MCA) and temporarily occluding it at one or more distinct locations, preferably three distinct locations. The model results in highly reproducible and focal infarct sizes, with low rate of mortality during the experimental procedure.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: July 21, 2015
    Assignee: UNIVERSITY OF PRINCE EDWARD ISLAND
    Inventors: Barry James Connell, Tarek Saleh
  • Apocynin-lipoic acid conjugates and uses thereof
    Patent number: 9012492
    Abstract: The present application relates to novel apocynin-lipoic acid covalent conjugates, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions that are mediated by oxidative stress. In particular, the present application includes compounds of Formula (I), and compositions and uses thereof.
    Type: Grant
    Filed: November 15, 2012
    Date of Patent: April 21, 2015
    Assignee: University of Prince Edward Island
    Inventors: Tarek Saleh, Desikan Rajagopal, Bobby Khan, Barry James Connell
  • APOCYNIN-LIPOIC ACID CONJUGATES AND USES THEREOF
    Publication number: 20140315989
    Abstract: The present application relates to novel apocynin-lipoic acid covalent conjugates, compositions comprising these compounds and their use, in particular for the treatment of diseases, disorders or conditions that are mediated by oxidative stress. In particular, the present application includes compounds of Formula (I), and compositions and uses thereof.
    Type: Application
    Filed: November 15, 2012
    Publication date: October 23, 2014
    Inventors: Tarek Saleh, Desikan Rajagopal, Bobby Khan, Barry James Connell
  • ANIMAL STROKE MODEL
    Publication number: 20120322096
    Abstract: An animal stroke model is provided. The model is useful in the study of brain ischemia and/or reperfusron injury and in identification and testing of compounds and interventions useful in the treatment of stroke. The method is carried out in a non-human mammal, such as rat. The method of inducing ischemia and/or reperfusion injury involves exposing a portion of the middle cerebral artery (MCA) and temporarily occluding it at one or more distinct locations, preferably three distinct locations. The model results in highly reproducible and focal infarct sizes with low rate of mortality during the experimental procedure.
    Type: Application
    Filed: February 16, 2011
    Publication date: December 20, 2012
    Applicant: UNIVERSITY OF PRINCE EDWARD ISLAND
    Inventors: Barry James Connell, Tarek Saleh