Patents by Inventor Barry Joseph Hand
Barry Joseph Hand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11130823Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: GrantFiled: January 27, 2020Date of Patent: September 28, 2021Assignee: Gelesis LLCInventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Publication number: 20200332025Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: ApplicationFiled: January 27, 2020Publication date: October 22, 2020Inventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Patent number: 10544233Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: GrantFiled: April 27, 2016Date of Patent: January 28, 2020Assignee: Gelesis LLCInventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Publication number: 20160319042Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: ApplicationFiled: April 27, 2016Publication date: November 3, 2016Inventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Patent number: 9353191Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: GrantFiled: June 7, 2012Date of Patent: May 31, 2016Assignee: Gelesis LLCInventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Publication number: 20130089737Abstract: The present invention provides a method of producing a polymer hydrogel comprising the steps of: (1) preparing an aqueous solution of a water soluble polysaccharide derivative and a polycarboxylic acid; (2) optionally agitating the solution, for example, by stirring; (3) isolating a polysaccharide derivative/polycarboxylic acid composite from the solution; and (4) heating the polysaccharide derivative/polycarboxylic acid composite at a temperature of at least about 80° C., thereby cross-linking the polysaccharide with the polycarboxylic acid. The invention also provides polymer hydrogels produced by the methods of the invention.Type: ApplicationFiled: June 7, 2012Publication date: April 11, 2013Inventors: Alessandro Sannino, Christian Demitri, Yishai Zohar, Barry Joseph Hand, Eyal S. Ron
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Patent number: 6013698Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: October 5, 1998Date of Patent: January 11, 2000Assignee: MedLogic Global CorporationInventors: E. C. Lupton, Xiaohong Yu, Lev Bromberg, Barry Joseph Hand
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Patent number: 5932285Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: February 17, 1995Date of Patent: August 3, 1999Assignee: MedLogic Global CorporationInventors: E. C. Lupton, Xiaohong Yu, Lev Bromberg, Barry Joseph Hand
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Patent number: 5849412Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: June 7, 1995Date of Patent: December 15, 1998Assignee: MedLogic Global CorporationInventors: Lev Bromberg, Elmer C. Lupton, Jr., Barry Joseph Hand
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Patent number: 5789494Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: June 7, 1995Date of Patent: August 4, 1998Assignee: Medlogic Global CorporationInventors: Barry Joseph Hand, E. C. Lupton, Jr., Lev Bromberg, Xiaohong Yu
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Patent number: 5726456Abstract: Methods and compositions for encapsulated polymeric gels swollen with nonaqueous reactive materials are provided. The methods include gel synthesis, swelling of a gel precursor with a first nonaqueous reactive material, and encapsulation of the swollen gel with a second nonaqueous reactive material. Gels precursors may be synthesized from crosslinking polymers, or alternatively, may be formed by crosslinking and polymerizing a monomer starting material. An accelerator may be utilized to facilitate swelling of the gel precursor with the first nonaqueous reactive material. Foams and composites may also be swollen with the first nonaqueous reactive material. The swollen gel is then contacted with a second nonaqueous reactive material such that an encapsulation layer is formed thereby. The encapsulated gels may be stored for subsequent use.Type: GrantFiled: June 7, 1995Date of Patent: March 10, 1998Assignee: Gel Sciences, Inc.Inventors: E. Cornelius Lupton, Xiaohong Yu, Lev Bromberg, Barry Joseph Hand