Patents by Inventor Barry L. Engelstad

Barry L. Engelstad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Contrast agents for magnetic resonance imaging of the small intestine and hepatobiliary system
    Patent number: 5382421
    Abstract: A method is provided utilizing contrast agents which provide increased diagnostic information in the magnetic resonance image of the hepatobiliary system and alimentary tract, especially the small intestine. Novel contrast agents which are N-carboxylated desferrioxamine B complexes with metal ions are provided.
    Type: Grant
    Filed: September 17, 1993
    Date of Patent: January 17, 1995
    Assignee: The Regents of the University of California
    Inventors: David L. White, Barry L. Engelstad, Kurt Muetterties
  • Imaging agents for in vivo magnetic resonance and scintigraphic imaging
    Patent number: 5010191
    Abstract: Methods are provided for in vivo magnetic resonance imaging and/or scintigraphic imaging of a subject using chelated transition metal and lanthanide metal complexes. Novel ligands for these complexes are provided.
    Type: Grant
    Filed: August 19, 1985
    Date of Patent: April 23, 1991
    Assignee: The Regents of the University of California
    Inventors: Barry L. Engelstad, Kenneth N. Raymond, John P. Huberty, David L. White
  • Contrast agents for magnetic resonance imaging of the small intestine and hepatobiliary system
    Patent number: 4999445
    Abstract: A method is provided utilizing contrast agents which provide increased diagnostic information in the magnetic resonance image of the hepatobiliary system and alimentary tract, especially the small intestine. Novel contrast agents which are N-carboxylated desferrioxamine B complexes with metal ions are provided.
    Type: Grant
    Filed: June 10, 1988
    Date of Patent: March 12, 1991
    Assignee: The Regents of the University of California
    Inventors: David L. White, Barry L. Engelstad, Kurt A. Muetterties
  • Contrast agents for nuclear magnetic resonance imaging
    Patent number: 4972837
    Abstract: A method is provided for obtaining in vivo differentiation of tissues in an animal by nuclear magnetic resonance imaging comprising the steps of introducing into the animal a complex comprising a paramagnetic metal ion and a chelator.
    Type: Grant
    Filed: September 16, 1987
    Date of Patent: November 27, 1990
    Assignee: Regents of the University of California
    Inventors: Barry L. Engelstad, Robert C. Brasch, Robert S. Hattner, George Wesbey, John P. Huberty
  • Therapy agents, methods of preparation, and methods of use
    Patent number: 4970061
    Abstract: New radiopharmaceutical compositions for use in nuclear medicine comprise radioastatinated benzylguanidine and radioastatinated carboxamidino phenylpiperazine. These compositions are used for treatment of disease, including neuroendocrine tumors, and specifically neuroblastoma.
    Type: Grant
    Filed: January 12, 1990
    Date of Patent: November 13, 1990
    Assignee: The Regents of the University of California
    Inventors: Barry L. Engelstad, David L. White, John P. Huberty
  • Method for attaining in vivo tissue-specific contrast by nuclear magnetic resonance imaging
    Patent number: 4909257
    Abstract: A method is provided for obtaining in vivo diferentiation of tissues in an animal by nuclear magnetic resonance imaging comprising the steps of introducing into the animal a complex comprising a paramagnetic ferric ion and a chelator. Particular contrast agents, Fe(HBED) and Fe(EHPG), are excretable by a hepatobiliary pathway.
    Type: Grant
    Filed: April 28, 1989
    Date of Patent: March 20, 1990
    Assignee: The Regents of the University of California
    Inventors: Barry L. Engelstad, Robert C. Brasch, Robert S. Hattner, George Wesbey, John P. Huberty
  • Therapy agents, methods of preparation, and methods of use
    Patent number: 4894218
    Abstract: New radiopharmaceutical compositions for use in nuclear medicine comprise radioastatinated benzylguanidine and radioastatinated carboxamidino phenylpiperazine. These compositions are used for treatment of disease, including neuroendocrine tumors, and specifically neuroblastoma.
    Type: Grant
    Filed: May 31, 1988
    Date of Patent: January 16, 1990
    Assignee: Regents of the University of California
    Inventors: Barry L. Engelstad, David L. White, John P. Huberty