Patents by Inventor Barry Lee Dowell

Barry Lee Dowell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method for identifying a hook effect and expanding the dynamic range in point of care immunoassays
    Patent number: 9671398
    Abstract: The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample.
    Type: Grant
    Filed: December 27, 2013
    Date of Patent: June 6, 2017
    Assignee: Abbott Point of Care Inc.
    Inventors: John Campbell, Linda Nguyen, James Smith, Wenda Weiss, Barry Lee Dowell
  • Antibodies relating to PIVKA-II and uses thereof
    Patent number: 9120862
    Abstract: The present disclosure relates to antibodies and immunoassay methods for use in the diagnosis, treatment and prevention of hepatocellular carcinoma (HCC), liver cancer and related conditions.
    Type: Grant
    Filed: July 26, 2010
    Date of Patent: September 1, 2015
    Assignees: ABBOTT LABORATORIES, ABBOTT JAPAN
    Inventors: Toru Yoshimura, Barry Lee Dowell, Gangamani S. Beligere, Eisaku Yoshida
  • APPARATUS AND METHOD FOR IDENTIFYING A HOOK EFFECT AND EXPANDING THE DYNAMIC RANGE IN POINT OF CARE IMMUNOASSAYS
    Publication number: 20140186216
    Abstract: The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample.
    Type: Application
    Filed: December 27, 2013
    Publication date: July 3, 2014
    Applicant: Abbott Point of Care Inc.
    Inventors: John Campbell, Linda Nguyen, James Smith, Wenda Weiss, Barry Lee Dowell
  • ANTIBODIES RELATING TO PIVKA-II AND USES THEREOF
    Publication number: 20120020972
    Abstract: The present disclosure relates to antibodies and immunoassay methods for use in the diagnosis, treatment and prevention of hepatocellular carcinoma (HCC), liver cancer and related conditions.
    Type: Application
    Filed: July 26, 2010
    Publication date: January 26, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Toru Yoshimura, Barry Lee Dowell, Gangamani S. Beligere, Eisaku Yoshida
  • Prostate specific antigen peptides and uses thereof
    Patent number: 6143509
    Abstract: The present invention relates to peptides which may be used, for example, in the detection of free and complexed Prostate Specific Antigen and thus in the diagnosis of prostate cancer.
    Type: Grant
    Filed: February 6, 1996
    Date of Patent: November 7, 2000
    Assignee: Abbott Laboratories
    Inventors: Barry Lee Dowell, Dominique P. Bridon, Xiaoxing Qiu, Hans Lilja, Timo Petteri Piironen, Mauno Antero Vihinen, Kim Sverker Immanuel Pettersson