Abstract: A sealing element for positioning radially outwardly of aerofoil blades of a gas turbine engine is provided. A radially inner surface region of the sealing element includes a seal structure having one or more inwardly projecting walls formed by additive layer, powder fed, laser weld deposition. The walls form a plurality of curved profile shapes which are arranged in a repeating pattern across the radially inner surface region. None of the walls intersects with any other wall. The curved profile shapes have no radii of curvature less than 0.5 mm.

Abstract: A sealing element for positioning radially outwardly of aerofoil blades of a gas turbine engine is provided. A radially inner surface region of the sealing element includes a seal structure having one or more inwardly projecting walls formed by additive layer, powder fed, laser weld deposition. The walls form a plurality of curved profile shapes which are arranged in a repeating pattern across the radially inner surface region. None of the walls intersects with any other wall. The curved profile shapes have no radii of curvature less than 0.5 mm.

Abstract: A spinosyn or a physiologically acceptable derivative or salt thereof for promoting or accelerating wound healing in humans.

Abstract: The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lactone. The invention also relates to the use of the active composition in pesticidal formulations, the formulations themselves and to the various applications of those formulations as pesticides, specifically in controlling all species of Phthiraptera, Siphonaptera and Acarina pests, typically in domestic animals. Such applications include the control of such external Phthiraptera, Siphonaptera and Acarina pests in domestic animals including but not limited to sheep, cattle, poultry, pigs, goats, camelids, horses, dogs and cats.

Abstract: The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lactone. The invention also relates to the use of the active composition in pesticidal formulations, the formulations themselves and to the various applications of those formulations as pesticides, specifically in controlling all species of Phthiraptera, Siphonaptera and Acarina pests, typically in domestic animals. Such applications include the control of such external Phthiraptera, Siphonaptera and Acarina pests in domestic animals including but not limited to sheep, cattle, poultry, pigs, goats, camelids, horses, dogs and cats.

Abstract: The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lactone. The invention also relates to the use of the active composition in pesticidal formulations, the formulations themselves and to the various applications of those formulations as pesticides, specifically in controlling all species of Phthiraptera, Siphonaptera and Acarina pests, typically in domestic animals. Such applications include the control of such external Phthiraptera, Siphonaptera and Acarina pests in domestic animals including but not limited to sheep, cattle, poultry, pigs, goats, camelids, horses, dogs and cats.

Abstract: A spinosyn or a physiologically acceptable derivative or salt thereof for promoting or accelerating wound healing in humans.

Abstract: A spinosyn or a physiologically acceptable derivative or salt thereof for promoting or accelerating wound healing in humans.

Abstract: The present invention relates to a device for applying a liquid pesticidal formulation to an external surface of a domestic animal, the device comprising an inlet and a plurality of spaced apart outlets, wherein the device is adapted such that when the middle of the device is positioned substantially above the spine of the animal, at least one outlet is positioned substantially above each flank of the animal. The invention also relates to a method for the treatment or prophylaxis of parasitic infestations, including ectoparasitic and/or endoparasitic infestations, of domestic animals comprising topically administering to said animal a pour-on pesticidal formulation to a region of the external surface of an animal extending from one flank to the opposing flank.

Abstract: The present invention relates to a device for applying a liquid pesticidal formulation to an external surface of a domestic animal, the device comprising an inlet and a plurality of spaced apart outlets, wherein the device is adapted such that when the middle of the device is positioned substantially above the spine of the animal, at least one outlet is positioned substantially above each flank of the animal. The invention also relates to a method for the treatment or prophylaxis of parasitic infestations, including ectoparasitic and/or endoparasitic infestations, of domestic animals comprising topically administering to said animal a pour-on pesticidal formulation to a region of the external surface of an animal extending from one flank to the opposing flank.

Abstract: The present invention relates to an active composition for controlling or eradicating Diptera pests in domestic animals or their environs, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lactone. The invention also relates to the use of the active composition in pesticidal formulations, the formulations themselves and to the various applications of those formulations as pesticides, specifically in controlling all species of Diptera pests in domestic animals or their environs. Such applications include the control of such external Diptera pests in domestic animals including but not limited to sheep, cattle, poultry, pigs, goats, camelids, horses, dogs and cats, and also the household and rural applications of such formulations in control of such pests.

Abstract: An improved rupture disk assembly and methods and apparatuses for forming a rupture disk are disclosed. The rupture disk assembly includes a rupture disk having a flange connected to a dome-shaped rupturable portion by a transition area. The rupturable portion includes a structural apex formation at or near the apex of the dome and is configured to rupture when exposed to a fluid having a predetermined pressure. Preferably, a safety member is disposed adjacent the rupture disk. The safety member includes a hinge about which the disk bends when the disk ruptures. The present invention is also directed to an apparatus and method for consistently, accurately, and repeatably forming a structural apex formation in a rupture disk before the formation of to the rupture disk dome, during the formation of the rupture disk dome, and after the formation of the rupture disk dome.

Abstract: An improved rupture disk assembly and methods and apparatuses for forming a rupture disk are disclosed. The rupture disk assembly includes a rupture disk having a flange connected to a dome-shaped rupturable portion by a transition area. The rupturable portion includes a structural apex formation at or near the apex of the dome and is configured to rupture when exposed to a fluid having a predetermined pressure. Preferably, a safety member is disposed adjacent the rupture disk. The safety member includes a hinge about which the disk bends when the disk ruptures. The present invention is also directed to an apparatus and method for consistently, accurately, and repeatably forming a structural apex formation in a rupture disk before the formation of the rupture disk dome, during the formation of the rupture disk dome, and after the formation of the rupture disk dome.

Abstract: A dry composition of an ionophore antibiotic such as monensin comprising

Abstract: An improved rupture disk assembly and methods and apparatuses for forming a rupture disk are disclosed. The rupture disk assembly includes a rupture disk having a flange connected to a dome-shaped rupturable portion by a transition area. The rupturable portion includes a structural apex formation at or near the apex of the dome and is configured to rupture when exposed to a fluid having a predetermined pressure. Preferably, a safety member is disposed adjacent the rupture disk. The safety member includes a hinge about which the disk bends when the disk ruptures. The present invention is also directed to an apparatus and method for consistently, accurately, and repeatably forming a structural apex formation in a rupture disk before the formation of the rupture disk dome, during the formation of the rupture disk dome, and after the formation of the rupture disk dome.

Abstract: An improved rupture disk assembly and methods and apparatuses for forming a rupture disk are disclosed. The rupture disk assembly includes a rupture disk having a flange connected to a dome-shaped rupturable portion by a transition area. The rupturable portion includes a structural apex formation at or near the apex of the dome and is configured to rupture when exposed to a fluid having a predetermined pressure. Preferably, a safety member is disposed adjacent the rupture disk. The safety member includes a hinge about which the disk bends when the disk ruptures. The present invention is also directed to an apparatus and method for consistently, accurately, and repeatably forming a structural apex formation in a rupture disk before the formation of the rupture disk dome, during the formation of the rupture disk dome, and after the formation of the rupture disk dome.

Abstract: An improved rupture disk assembly and methods and apparatuses for forming a rupture disk are disclosed. The rupture disk assembly includes a rupture disk having a flange connected to a dome-shaped rupturable portion by a transition area. The rupturable portion includes a structural apex formation at or near the apex of the dome and is configured to rupture when exposed to a fluid having a predetermined pressure. Preferably, a safety member is disposed adjacent the rupture disk. The safety member includes a hinge about which the disk bends when the disk ruptures. The present invention is also directed to an apparatus and method for consistently, accurately, and repeatably forming a structural apex formation in a rupture disk before the formation of to the rupture disk dome, during the formation of the rupture disk dome, and after the formation of the rupture disk dome.

Abstract: An improved rupture disk assembly for a pressure relief system is disclosed. The rupture disk assembly is sealed between an inlet support member and an outlet support member, each of which define a central fluid pathway. A rupture disk that includes a flange connected to a dome-shaped rupturable portion by a transition area is sealed between the support members. The rupturable portion may include an indentation positioned at the apex of the dome and a score line having a first and a second end. A safety member that has a hinge including a knuckle and a tongue is positioned between the rupture disk and the outlet support member. The knuckle extends downwardly into the dome and extends laterally across the dome to a point that is inside the area circumscribed by the score line or inside the area circumscribed by an arc connecting the two ends of the score line.

Abstract: An aqueous base suspension concentrate of an ionophore antibiotic or ionophore antibiotics capable of aqueous dilution (if desired) and capable (with or without such aqueous dilution) of being orally administered to an animal (eg; by drenching), said concentration comprising(I) at least one ionophore antibiotic in (II) an aqueous system containing( ) a wetting and/or surfactant agent(ii) an antifreeze agent or agents in which the ionophore antibiotic or antibiotics is or are no more than sparingly soluble,(iii) a suspension agent,(iv) optionally an antifoam agent or system,(v) optionally a preservative,(vi) optionally a de-bittering agent,(vii) optionally a pH buffering system, and(viii) water.