Patents by Inventor Barry N. Newton

Barry N. Newton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4175544
    Abstract: A method for using iodo-aryl carbonates, such as for example, p-iodo-benzyl carbonates, p-iodo-sec-phenethyl carbonates, p-iodo-phenethyl carbonates, p-iodo-phenyl carbonates, 3-(p-iodophenyl)propyl carbonates, 3-(p-iodophenyl)butyl carbonates, 2-(p-iodobenzyl)butyl carbonates and 2-(p-iodobenzyl)-n-hexyl carbonates, to provide radiopaques for various radiography purposes in connection with such techniques as X-ray applications including myelography, salpingography, lymphography and bronchography. The method first comprises selecting a compound generally categorized as a carbonate and having the general formula ##STR1## wherein R represents an alkyl group having from 1 to 10 carbon atoms and R' represents an iodinated phenyl linked directly to the ester oxygen or through an alkyl chain consisting of 1 to 3 carbon atoms. An effective amount of a pharmaceutically acceptable carbonate, as defined herein, is then placed into the subject body cavity and the particular X-ray or other study performed of this area.
    Type: Grant
    Filed: June 28, 1978
    Date of Patent: November 27, 1979
    Assignee: Lafayette Pharmacal Inc.
    Inventor: Barry N. Newton
  • Patent number: 4125554
    Abstract: Iodinated thiolcarbonates and a method for using the same as radiographic contrast agents in connection with such X-ray techniques as myleography, lymphography, hysterosalpingography, bronchography and sialography. The general formula of such iodonated thiolcarbonate compounds may be characterized as ##STR1## wherein R represents an iodinated phenyl linked to the sulfur through a lower alkylene group consisting of a straight or branched chain having from 1 to 5 carbon atoms and R.sub.1 is a lower alkyl group consisting of a straight or branched chain having from 1 to 10 carbon atoms.
    Type: Grant
    Filed: September 23, 1977
    Date of Patent: November 14, 1978
    Assignee: Alcon Laboratories, Inc.
    Inventor: Barry N. Newton
  • Patent number: 4022814
    Abstract: Iodo-aryl carbonates, such as for example, p-iodo-benzyl carbonates, p-iodo-sec-phenethyl carbonates, p-iodo-phenethyl carbonates, p-iodo-phenyl carbonates, 3-(p-iodophenyl)propyl carbonates, 3-(p-iodophenyl)butyl carbonates, 2-(p-iodobenzyl)butyl carbonates and 2-(p-iodobenzyl)-n-hexyl carbonates, for use as radiographic media in connection with such techniques as x-ray applications including myelography, salpingography, lymphography and bronchography. An effective quantity of iodinated organic carbonate provides x-ray contrast, and the compounds of the invention may be characterized generally as carbonates having the general formula ##STR1## wherein R represents an alkyl group having from 4 to 10 carbon atoms and R' represents an iodinated phenyl linked to the ester oxygen through an alkyl chain consisting of 1 to 3 carbon atoms.
    Type: Grant
    Filed: April 22, 1976
    Date of Patent: May 10, 1977
    Assignee: Lafayette Pharmacal, Inc.
    Inventor: Barry N. Newton