Patents by Inventor Barry Neil Silberg

Barry Neil Silberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11197987
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: December 14, 2021
    Inventor: Barry Neil Silberg
  • Patent number: 11129977
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: September 28, 2021
    Inventors: Barry Neil Silberg, Seth Putterman
  • Publication number: 20190308037
    Abstract: An ultrasound applicator designed to turn off an ultrasound system when an application area has reached too high of a temperature may include an ultrasound head; and a temperature sensor operatively attached to the ultrasound head and to the ultrasound delivery system. When the temperature sensor senses a temperature above a predetermined value, the ultrasound system may shuts off. The ultrasound applicator may additionally include an electronic module, wherein the temperature sensor is operatively connected to the electronic module which is operatively connected to the ultrasound deliver unit, and the electronic module includes a temperature controlled switch designed to turn off power to the ultrasound delivery unit when the temperature sensor senses the temperature above the predetermined value.
    Type: Application
    Filed: October 25, 2017
    Publication date: October 10, 2019
    Inventor: Barry Neil Silberg
  • Publication number: 20190209824
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Application
    Filed: March 18, 2019
    Publication date: July 11, 2019
    Applicant: Sonescence, Inc.
    Inventors: Barry Neil Silberg, Seth Putterman
  • Patent number: 10258782
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Grant
    Filed: March 31, 2018
    Date of Patent: April 16, 2019
    Assignee: Sonescence, Inc.
    Inventors: Barry Neil Silberg, Seth Putterman
  • Publication number: 20190070398
    Abstract: Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.
    Type: Application
    Filed: October 29, 2018
    Publication date: March 7, 2019
    Inventor: Barry Neil Silberg
  • Patent number: 10137290
    Abstract: Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: November 27, 2018
    Assignee: Sonescence, Inc.
    Inventor: Barry Neil Silberg
  • Patent number: 10099045
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Grant
    Filed: May 29, 2015
    Date of Patent: October 16, 2018
    Assignee: Sonescence, Inc.
    Inventor: Barry Neil Silberg
  • Publication number: 20180221638
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Application
    Filed: March 31, 2018
    Publication date: August 9, 2018
    Inventors: Barry Neil Silberg, Seth Putterman
  • Patent number: 9956388
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Grant
    Filed: June 4, 2015
    Date of Patent: May 1, 2018
    Assignee: Sonescence, Inc.
    Inventors: Barry Neil Silberg, Seth Putterman
  • Patent number: 9446227
    Abstract: Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: September 20, 2016
    Assignee: Sonescence, Inc.
    Inventor: Barry Neil Silberg
  • Publication number: 20160015953
    Abstract: According to some embodiments herein, systems for delivering therapeutic agents and/or methods of using such systems are provided. The systems can be configured to administer solution comprising therapeutic agent to a subject, and can further comprise an ultrasound applicator for applying ultrasound energy to the subject.
    Type: Application
    Filed: June 4, 2015
    Publication date: January 21, 2016
    Inventor: Barry Neil Silberg
  • Publication number: 20150297879
    Abstract: Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.
    Type: Application
    Filed: May 29, 2015
    Publication date: October 22, 2015
    Inventor: Barry Neil Silberg
  • Publication number: 20150273198
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Application
    Filed: June 12, 2015
    Publication date: October 1, 2015
    Inventor: Barry Neil Silberg
  • Publication number: 20150258320
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Application
    Filed: May 29, 2015
    Publication date: September 17, 2015
    Inventor: Barry Neil Silberg
  • Publication number: 20140288483
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventor: Barry Neil Silberg
  • Patent number: 8747384
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: June 10, 2014
    Inventor: Barry Neil Silberg
  • Publication number: 20120123321
    Abstract: Therapeutic agents, diagnostic agents and other compositions can be effectively delivered to target tissues using ultrasonic dispersion. For example, a therapeutic agent in solution may be injected subcutaneously in the vicinity of a target tissue in a patient. External ultrasound is used to disperse the therapeutic agent in the target tissue. The disclosed methods provide increased concentrations of therapeutic agents in tissue relative to traditional delivery methods, thereby improving therapeutic outcomes while reducing costs. In addition the methods can be used to deliver effective concentrations of therapeutic agents to tissues with limited blood supply.
    Type: Application
    Filed: December 15, 2011
    Publication date: May 17, 2012
    Inventor: Barry Neil Silberg
  • Publication number: 20110301528
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 8, 2011
    Inventor: Barry Neil Silberg
  • Publication number: 20100069827
    Abstract: Antibiotics are administered in a surgical site subcutaneously via a small or stab incision in the surgical field. Transcutaneous ultrasonic vibrations are applied across the surgical field, which is then opened in the usual manner, to thereby provide a surgical field which contains a vastly higher and more effective level of antibiotic. At the same time the underlying tissue is hydrated.
    Type: Application
    Filed: March 17, 2009
    Publication date: March 18, 2010
    Inventor: Barry Neil Silberg