Abstract: A guide extension catheter assembly including a guide extension catheter and a support device. The guide extension catheter includes a shaft and a tubular member. The support device includes a push member and a shuttle member. The guide extension catheter assembly is configured to selectively provide a delivery state in which at least a portion of the shuttle member is disposed within the lumen, a leading end of the shuttle member is distal a distal end of the tubular member, and the shuttle member is directly, physically connected to the tubular member. In the delivery state, a longitudinal distal force applied to the push member is transferred to the tubular member as a longitudinal distal force via the shuttle member. The guide extension catheter assemblies of the present disclosure can promote a two stage guide extension catheter deployment.

Abstract: Describes is a battery booster for jumpstarting a vehicle having an external battery. The battery booster comprising a set of electrical conductors, a power supply configured to supply a starting current to jump start the vehicle via the set of electrical conductors, a boost switch positioned in-line between the power supply and a set of battery clamps on one of the set of electrical conductors; and at least one processor configured to output a control signal to close the boost switch as a function of one or more parameters of the power supply, the external battery, or the vehicle. The set of electrical conductors are configured to couple with the external battery or with an engine that is electrically coupled with the external battery via the set of battery clamps. The set of electrical conductors comprises a positive electrical conductor and a negative electrical conductor.

Abstract: A guide extension catheter assembly including a guide extension catheter and a support device. The guide extension catheter includes a shaft and a tubular member. The support device includes a push member and a shuttle member. The guide extension catheter assembly is configured to selectively provide a delivery state in which at least a portion of the shuttle member is disposed within the lumen, a leading end of the shuttle member is distal a distal end of the tubular member, and the shuttle member is directly, physically connected to the tubular member. In the delivery state, a longitudinal distal force applied to the push member is transferred to the tubular member as a longitudinal distal force via the shuttle member. The guide extension catheter assemblies of the present disclosure can promote a two stage guide extension catheter deployment.

Abstract: An update device for providing configuration updates, such as recipes, advertising content, software update(s), pricing updates and/or other changes to brewer parameters, to a brewer device. When turned on, the update device wirelessly connects to a cloud account associated with the brewer device. Any pending content updates associated with the cloud account are wirelessly delivered to the update device and stored. When the update device is connected to the brewer device, the update device emulates a disk drive to transfer the updates to the brewer device.

Abstract: A catheter for measuring a fractional flow reserve includes a proximal shaft, a distal shaft coupled to a distal portion of the proximal shaft, and a pressure sensor coupled to the distal shaft. The proximal shaft includes a distal portion configured to extend through a stenosis in a vessel. The distal portion of the proximal shaft includes a radially expanded configuration having a first diameter and a radially collapsed configuration having a second diameter, wherein the first diameter is larger than the second diameter. The distal shaft includes a guidewire lumen configured to receive therein.

Abstract: A device for depositing layers on flat substrates includes a susceptor which can be heated by a heating device. The substrates and cover plates enclosing same are arranged on an upper face of the susceptor facing a process chamber. The cover plates include inner cover plates, each of which forms an edge adjoining a substrate edge facing the center of the susceptor. The inner cover plates are arranged about the center of the susceptor in the circumferential direction, and adjacent ones of the inner cover plates adjoin each other at a separation joint. The separation joint is arranged at an angle ? to a line which extends through the center of the susceptor and the center of one of the substrates in a radial direction.

Abstract: A susceptor assembly, which is situated in a reactor housing, has at least one wide side plane that faces a process chamber, at least one pocket, and a carrying element that lies in the at least one pocket, for carrying and handling a substrate. An upper face of the carrying element is adjacent to a limiting face of a recess in which the substrate is arranged. A section of the limiting face which runs along a cylinder inner lateral face merges into the upper face of the carrying element, forming a rounded edge or chamfer. To reduce the growth of parasitic deposits on an inner edge of the carrying element, the section of the limiting face which runs along the cylinder inner lateral face has a height which is greater than the material thickness of the substrate, and the radius of the rounded edge is greater than 0.4 mm.

Abstract: Treating patients with therapeutically effective electroporation requires the use of voltage potentials which when applied to the patient can be painful due to the noxious overstimulation of the afferent pain-receptive nerve fibres. An electrode assembly which includes electrodes for applying effective electroporation voltages, also comprises at least one electrode configured to apply a non-noxious, non-painful electrical stimulation which may be referred to as a “nerve block adjacent to the electroporation site.

Abstract: An update device for providing configuration updates, such as recipes, advertising content, software update(s), pricing updates and/or other changes to brewer parameters, to a brewer device. When turned on, the update device wirelessly connects to a cloud account associated with the brewer device. Any pending content updates associated with the cloud account are wirelessly delivered to the update device and stored. When the update device is connected to the brewer device, the update device emulates a disk drive to transfer the updates to the brewer device.

Abstract: Various methods are provided for programmatically providing a platform for responding dynamically providing a response to a property level availability call through API request based on run-time information. One example method may comprise receiving the property level availability call, the property level availability call configured to elicit a response identifying an availability of one or more of the plurality of specified properties for a specified time frame, determining, based on an associated bid, whether an affirmative response to the property level availability call is profitable, and in an instance in which the affirmative response is profitable, causing transmission of the affirmative response.

Abstract: A balloon guide catheter system including a balloon guide catheter having a catheter shaft that includes: (i) a main lumen; (ii) an inflation lumen; and (iii) an exhaust lumen. The terminating distal end of the inflation lumen and the terminating distal end of the exhaust lumen being in localized fluid communication with one another underneath the balloon while in a non-inflated state. A balloon is disposed about a distal region of an outer surface of the catheter shaft. The exhaust lumen is configured to purge the residual air in a proximal direction and out from a proximal region of the balloon guide catheter.

Abstract: An example modular imaging system may include at least a modular imaging enclosure and a power supply. The modular imaging enclosure may include multiple panels coupled together to define an interior space of the modular imaging enclosure where an object may be placed in order to obtain image data relating to the object. Individual ones of the panels may include imaging panels having one or more light emitting elements, an array of cameras, and a panel computer. The power supply can supply power to these electronic components so they can operate to capture images of an object in appropriate lighting. The modular nature of the imaging system allows for easy packaging and shipment, as well as easy setup and teardown to use the imaging system, making it an easily transportable device that can be easily transported to the location of an object(s) to be imaged.

Abstract: Transcatheter delivery systems, delivery catheters and associated methods for percutaneous delivery of prosthetic mitral valves using a retrograde approach are disclosed herein. A heart valve delivery system configured in accordance herewith includes a delivery catheter having an elongated tubular component and an articulation assembly at a distal end thereof. The articulation assembly includes an arm portion coupled to the tubular component by an elbow or hinge portion. In a closed, delivery state, the elbow portion positions the arm portion generally parallel to the tubular component for delivery of the delivery catheter through the vasculature. In an open, deployed state, the elbow portion positions the arm portion in a non-axial direction with respect to a longitudinal axis of the tubular component for orienting and positioning a prosthetic valve device carried by the arm portion, e.g., within the native mitral valve region.

Abstract: A system provides a listener application which can be notified about specific ports used by specific instances of a WebSocket application. A WebSocket application opens multiple dynamic ports in certain scenarios with a dynamic context. When an application is executed, a listener application is made aware of the context and port information. A system rewrites a reverse proxy configuration on the fly so that any request coming into the reverse proxy will read the change and assign the correct port. A notification to the listener is received across multiple nodes, and the configuration can be updated on all nodes based on the data provided in the configuration.

Abstract: An apparatus for localising an electrical field for electroporation of abluminal tissue such as ganglionated plexi is provided comprising a pulsed DC electrical power supply and at least two catheters. Each catheter includes at least one catheter tip and electrode assembly configured for endocardial placement such that the electrodes are positionable at separate endocardial locations and allow development of an electrical field between the electrodes to effect electroporation of the abluminal tissue in the electrical field.

Abstract: A tissue-removing catheter for removing tissue in a body lumen includes an elongate body having an axis and proximal and distal end portions spaced apart from one another along the axis. A turbine is fixed to the elongate body and is disposed at an intermediate position between the proximal and distal end portions of the elongate body. A rotatable tissue-removing element is at the distal end portion of the elongate body and is operatively coupled to the turbine such that the turbine imparts rotation of the tissue-removing element. The tissue-removing element removes the tissue from the body lumen as the tissue-removing element is rotated by the turbine.

Abstract: Transcatheter delivery systems, delivery catheters and associated methods for percutaneous delivery of prosthetic mitral valves using a retrograde approach are disclosed herein. A heart valve delivery system configured in accordance herewith includes a delivery catheter having an elongated tubular component and an articulation assembly at a distal end thereof. The articulation assembly includes an arm portion coupled to the tubular component by an elbow or hinge portion. In a closed, delivery state, the elbow portion positions the arm portion generally parallel to the tubular component for delivery of the delivery catheter through the vasculature. In an open, deployed state, the elbow portion positions the arm portion in a non-axial direction with respect to a longitudinal axis of the tubular component for orienting and positioning a prosthetic valve device carried by the arm portion, e.g., within the native mitral valve region.

Abstract: Various methods are provided for programmatically providing a platform for responding dynamically providing a response to a property level availability call through API request based on run-time information. One example method may comprise receiving the property level availability call, the property level availability call configured to elicit a response identifying an availability of one or more of the plurality of specified properties for a specified time frame, determining, based on an associated bid, whether an affirmative response to the property level availability call is profitable, and in an instance in which the affirmative response is profitable, causing transmission of the affirmative response.

Abstract: A guide extension catheter includes a proximal shaft, a distal shaft, and a plurality of perfusion openings. The distal shaft includes a jacket and a helical coil structure embedded in the jacket, the distal shaft defining a lumen. The plurality of perfusion openings are disposed though the jacket of the distal shaft between windings of the helical coil structure. The guide extension catheter provides additional back support to the guide catheter. The plurality of perfusion openings allow fluid communication between an area outside the guide extension catheter and the lumen.

Abstract: Medical devices for positioning a valve in a subject's body, such as a prosthetic heart valve in a subject's heart, are disclosed. The prosthetic heart valve may include a valve assembly, a frame, and a control arm. The prosthetic heart valve may include a commissural post or multiple commissural posts. The prosthetic heart valve may include a positional marker on a control arm. The prosthetic heart valve may include multiple positional markers on one or more control arms. The positional markers can be shapes, characters, or other symbols. The positional markers may themselves be asymmetric. The positional markers may be placed in an asymmetric location on a control arm. The control arm may be asymmetrically shaped.