Abstract: The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with Nrf2 activation.

Abstract: The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.

Abstract: The present invention relates to compounds that are antagonists of the orexin-1 receptor. The compounds have the structural formula (I) defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.

Abstract: The present invention relates to compounds that are IL-17A modulators. The compounds have the structural Formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with modulation of IL-17A activity.

Abstract: The present invention relates to compounds that are IL-17A modulators. The compounds have the structural Formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with modulation of IL-17A activity.

Abstract: The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with Nrf2 activation.

Abstract: The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.

Abstract: The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.

Abstract: A steering column system of a vehicle includes: a rotatable, hollow steering shaft that has a proximal end attached to a steering wheel and is configured to transfer rotational input at the steering wheel to a steering rack of the vehicle; a stationary driver-side airbag (DAB) shaft that is surrounded by the steering shaft and extends along the steering shaft; and a DAB module that contains an airbag and is fixedly mounted to a proximal end of the DAB shaft within a region of the steering wheel. The airbag contained in the DAB module is formed to have a substantially circular center chamber and a pair of side extension chambers, one of the side extension chambers disposed on a right side of the center chamber, and the other of the side extension chambers disposed on a left side of the center chamber.

Abstract: A steering column system includes: a rotatable steering shaft that has a proximal end attached to a steering wheel and is configured to transfer rotational input at the steering wheel to a steering rack of the vehicle; a stationary driver-side airbag (DAB) shaft that is mounted in the vehicle and extends along the steering shaft; and a DAB module that contains an airbag and is fixedly mounted to a proximal end of the DAB shaft within a region of the steering wheel. The steering wheel and the steering shaft are configured to rotate independently of the DAB module and the DAB shaft, respectively.

Abstract: The present invention relates to compounds that are inhibitors of the orexin-1 receptor. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with orexin-1 receptor activity.

Abstract: A steering column system includes: a rotatable steering shaft that has a proximal end attached to a steering wheel and is configured to transfer rotational input at the steering wheel to a steering rack of the vehicle; a stationary driver-side airbag (DAB) shaft that is mounted in the vehicle and extends along the steering shaft; and a DAB module that contains an airbag and is fixedly mounted to a proximal end of the DAB shaft within a region of the steering wheel. The steering wheel and the steering shaft are configured to rotate independently of the DAB module and the DAB shaft, respectively.

Abstract: A steering column system of a vehicle includes: a rotatable, hollow steering shaft that has a proximal end attached to a steering wheel and is configured to transfer rotational input at the steering wheel to a steering rack of the vehicle; a stationary driver-side airbag (DAB) shaft that is surrounded by the steering shaft and extends along the steering shaft; and a DAB module that contains an airbag and is fixedly mounted to a proximal end of the DAB shaft within a region of the steering wheel. The airbag contained in the DAB module is formed to have a substantially circular center chamber and a pair of side extension chambers, one of the side extension chambers disposed on a right side of the center chamber, and the other of the side extension chambers disposed on a left side of the center chamber.

Abstract: A slave strobe is built including a photodetector, a flash tube, a flash controller, a mode switch, a body, and a top rotatable with respect to the body, and depressible with respect to the body. The photodetector is configured to detect a flash of light. The flash controller is electrically coupled with the photodetector, the mode switch and the flash tube, and is configured to change modes of operation when the mode switch is activated. The mode switch is configured to activate when the top is depressed. The top includes a plurality of strobe lenses configured to modify a flash of light from the flash tube when rotated in front of the flash tube.

Abstract: A tripod is configured with a body configured to match the shape and size of the bottom of a camera. The tripod body optionally includes recesses allowing the three legs to fold up into the body, resulting in a substantially planar bottom surface. The three legs, when extended, are independently positionable to give the user the flexibility to use the tripod on non-planar surfaces, and to allow some aiming of the camera.

Abstract: A patient support platform provides a solution for healthcare facilities and nursing staff to address patient and staff safety, patient mobility, patient comfort, the availability of patient information, monitoring drugs and therapy provided, and controlling health care expenses. The patient support platform preferably includes a transmission system that allows the patient and/or medical staff member to choose a stop, walk or roll mode. The transmission system preferably includes a drag wheel for applying a braking force in response to a voltage generated by a braking motor. The platform supports a plurality of devices that may be attached or associated with a patient throughout their stay at a healthcare facility. The support platform also preferably includes a mechanism for releasably attaching the support platform to another structure, such as a bed. Embodiments of the present invention include multiple non-medical uses of the platform.