Patents by Inventor Barry Shearer

Barry Shearer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MrgX2 antagonists
    Patent number: 11976057
    Abstract: This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.
    Type: Grant
    Filed: October 4, 2021
    Date of Patent: May 7, 2024
    Assignee: GlaxoSmithKline Intellectual Property Development Limited
    Inventors: Edward Brnardic, Michael Bury, Rodolfo Cadilla, Jon Collins, Yu Guo, Anthony Handlon, Huijie Li, Yue Li, Daniel Paone, Christie Schulte, Barry Shearer, Maben Ying, Guosen Ye, Huichang Zhang, Millard Hurst Lambert, III
  • MRGX2 ANTAGONISTS
    Publication number: 20220112174
    Abstract: This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.
    Type: Application
    Filed: October 4, 2021
    Publication date: April 14, 2022
    Inventors: Edward BRNARDIC, Michael BURY, Rodolfo CADILLA, Jon COLLINS, Yu GUO, Anthony HANDLON, Huijie LI, Yue LI, Daniel PAONE, Christie SCHULTE, Barry SHEARER, Guosen YE, Maben YING, Huichang ZHANG
  • Chemical compounds
    Publication number: 20060148887
    Abstract: The present invention discloses compounds of Formula I. The present invention also discloses beta-3 agonists of formula I and methods for treating beta-3 mediated diseases and condition using the compounds of formula I, in particular methods for treating diabetes or obesity.
    Type: Application
    Filed: February 21, 2006
    Publication date: July 6, 2006
    Inventors: David Deaton, Barry Shearer, David Uehling
  • Wood products and processes for the preparation thereof
    Publication number: 20050038182
    Abstract: A process for treating wood comprising: a) impregnating the wood with a solution of furfuryl alcohol; b) allowing the impregnated wood to sit so as to permit diffusion of the furfuryl alcohol solution into the wood; and hot pressing the wood under conditions to effect polymerization of the furfuryl alcohol within the wood.
    Type: Application
    Filed: April 12, 2004
    Publication date: February 17, 2005
    Inventors: Branko Hermescec, Neli Drvodelic, Barry Shearer, David Butt, Brett Skewes
  • Method for treating inflammation and compounds and compositions suitable for use therein
    Patent number: 5079260
    Abstract: The present invention relates to a method of treating an inflammatory condition, and to compounds and composition suitable for use in such a method, which compounds have the Formula: ##STR1## wherein: X is methylene, ethylene, ethyleneoxy, or oxygen;Q is ##STR2## where C' is a residue of a lipophilic amino acid, and Y is --CO.sub.2 H, --CH.sub.2 OH, --CONR.sub.1 R.sub.2, or --CO.sub.2 R.sub.1 where R.sub.1 and R.sub.2 hydrogen, alkyl, or aryl;R.sub.3 and R.sub.4 are, independently, hydrogen, alkyl or aryl; andA and B are, independently, hydrogen, fused phenyl, alkyl, aryl, alkaryl, aralkyl, alkoxy, alkoxyalkyl, halogen, or nitro;or pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: January 7, 1992
    Assignee: Nova Pharmaceutical Corporation
    Inventors: Moshe Weitzberg, Ronald Burch, Barry Shearer