Abstract: Disclosed are implementations of systems and methods for generation and execution of hybrid decision trees for machine learning systems and processing environments. The systems include a data processing system for a computer memory, comprising means for configuring a memory device according to a hybrid decision tree, said hybrid decision tree including a plurality of nodes, each node comprising at least one directional associative link to or from another node, each node associated with a function performed on an input variable, wherein each directional associative link is agnostic to a hierarchical layer of the associated nodes in the hybrid decision tree; and means for executing functions associated with each node of the hybrid decision tree according to the corresponding directional associative links.