Patents by Inventor Bart Anderson

Bart Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220362398
    Abstract: The present application is directed to the intravitreal use of spherical nucleic acid (SNA) molecules in the treatment of eye disorders including dry-eye, retinal edema, retinopathy, macular degeneration and glaucoma among others. SNAs have a liposomal core with a plurality of oligonucleotides on the surface forming a shell, wherein the oligonucleotide preferably a TNF-alpha antisense oligonucleotide.
    Type: Application
    Filed: April 24, 2020
    Publication date: November 17, 2022
    Applicant: Exicure Operating Company
    Inventors: Bart Anderson, Richard Kang
  • Publication number: 20220064649
    Abstract: Aspects of the invention relate to compositions of spherical nucleic acids (SNAs) composed of a liposome or lipoplex complex having an oligonucleotide shell with CpG oligonucleotides positioned on the exterior of the liposome or lipoplex. The invention also relates to methods of treating subjects and of inducing cytokine expression in a subject using the compositions described herein.
    Type: Application
    Filed: April 15, 2021
    Publication date: March 3, 2022
    Applicant: Exicure, Inc.
    Inventors: Bart Anderson, Subbarao Nallagatla, Richard Kang, Ekambar Kandimalla
  • Publication number: 20210269806
    Abstract: The invention in some aspects relates to antisense inhibitors of IL1B and related methods of use. The antisense inhibitors may be formulated as a nanoparticle or other type of three dimensional presentation format.
    Type: Application
    Filed: June 20, 2019
    Publication date: September 2, 2021
    Applicant: Exicure, Inc.
    Inventor: Bart Anderson
  • Publication number: 20210002640
    Abstract: Compositions related to spherical nucleic acids (SNAs) and structures with antisense oligonucleotides and methods of treatment of diseases and disorders are disclosed herein.
    Type: Application
    Filed: February 28, 2019
    Publication date: January 7, 2021
    Applicant: Exicure, Inc.
    Inventors: Richard Kang, Subbarao Nallagatla, Bart Anderson, Ekambar Kandimalla, Michael Mutolo
  • Publication number: 20200297867
    Abstract: The invention relates to a method of synthesizing liposomes and liposomal spherical nucleic acids with hydrophobic molecules functionalized to the surface. The lipid particles contain one or more agents that elicit an immune response.
    Type: Application
    Filed: February 1, 2017
    Publication date: September 24, 2020
    Applicant: Exicure, Inc.
    Inventors: Richard Kang, Sagar Anantatmula, Rishika Agarwal, Merideth Burkhart, Bart Anderson
  • Publication number: 20200255837
    Abstract: Aspects of the invention relate to compositions of spherical nucleic acids (SNAs) composed of a liposome or lipoplex complex having an oligonucleotide shell with CpG oligonucleotides positioned on the exterior of the liposome or lipoplex. The invention also relates to methods of treating subjects and of inducing cytokine expression in a subject using the compositions described herein.
    Type: Application
    Filed: May 5, 2017
    Publication date: August 13, 2020
    Applicant: Exicure, Inc.
    Inventors: Bart Anderson, Subbarao Nallagatla, Richard Kang, Ekambar Kandimalla
  • Publication number: 20200248183
    Abstract: Aspects of the invention relate to immunostimulatory spherical nucleic acids (IS-SNA) for the treatment of a disorder, such as cancer. The IS-SNA may be administered together with a checkpoint inhibitor.
    Type: Application
    Filed: May 5, 2017
    Publication date: August 6, 2020
    Inventors: Subbarao Nallagatla, Bart ANDERSON, Ekambar KANDIMALLA
  • Publication number: 20200188521
    Abstract: Spherical nucleic acids (SNA) carrying self-aggregating oligonucleotides are described herein. Compositions of the SNA include discrete nanostructures that are not aggregated. Related methods are also described.
    Type: Application
    Filed: April 27, 2018
    Publication date: June 18, 2020
    Applicant: Exicure, Inc.
    Inventors: Richard Kang, Subbarao Nallagatla, Bart Anderson, Ekambar Kandimalla
  • Publication number: 20190225968
    Abstract: Aspects of the invention relate to compositions of spherical nucleic acids (SNAs) composed of a liposome or lipoplex complex having an oligonucleotide shell with CpG oligonucleotides positioned on the exterior of the liposome or lipoplex. The invention also relates to methods of treating subjects and of inducing cytokine expression in a subject using the compositions described herein.
    Type: Application
    Filed: May 5, 2017
    Publication date: July 25, 2019
    Applicant: Exicure, Inc.
    Inventors: Bart Anderson, Subbarao Nallagatla, Richard Kang, Ekambar Kandimalla
  • Publication number: 20190142739
    Abstract: Aspects of the invention relate to topical and ocular formulations of spherical nucleic acids (SNA), as well as methods of use thereof and compositions thereof.
    Type: Application
    Filed: April 13, 2017
    Publication date: May 16, 2019
    Applicant: Exicure, Inc.
    Inventors: Pinal Patel, Bart Anderson
  • Publication number: 20060063197
    Abstract: The use of fluorescent dye in printing buffer used to print spots of a protein microarray permits the presence, location and morphology of individual spots to be detected based on the fluorescent response of the spots. This information can be used to perform quality control of protein microarrays. In addition, the fluorescent response of the spots can prevent poor spots from being used in a protein assay or prevents faulty data from being accepted. The size of the spots can also be used to normalize the results obtained in a protein assay. The position of the spots can be used to establish anchors in detecting the chemiluminescent response of spots to which biological samples have been applied.
    Type: Application
    Filed: September 17, 2004
    Publication date: March 23, 2006
    Inventors: Bart Anderson, David Hall, Matthew Groll, Christopher Bingham, James Thompson, Rex Spendlove