Abstract: A chronology-centric, defined-knowledge-domain information-handling methodology supported by a system featuring (a) a dynamic EDP data repository, (b) plural EDP case-entity chronologies stored in the repository in the forms of respective, internally time-stamped and chronologically-organized groups of EDPs that effectively define, case-entity-specific, respectively different stage-and-time EDP-condition identities of particular domain-associated subject matter, and (c) data-processing engine structure connected to the repository for recurrently and progressively interacting with the data repository in relation to at least one of constructing, re-constructing, accessing, and reporting the respective organizations, contents and significances of, selected case-entity chronologies, as well, if user requested at a particular point in time, as performing, and output reporting user-sought information associated with, relevant, selected, time-and-stage EDP-content registry alignments between different case-entity ch