Patents by Inventor Bart Michael Eschler

Bart Michael Eschler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mannose-6-phosphonate compounds for the treatment of inflammatory diseases
    Patent number: 7648966
    Abstract: Novel phosphotetrahydropyran compounds that mimic mannose-6-phosphate but that are more resistant to phosphatases and mannosidases, and pharmaceutical compositions thereof, are disclosed. These compounds and compositions inhibit T lymphocyte migration from blood to tissues or to other extravascular sites. By inhibiting such migration, these compounds are useful for treating diseases or disorders that are mediated at least in part by such T lymphocyte migration. Such diseases and disorders include rheumatoid arthritis, multiple sclerosis, acute disseminated encephalomyelitis, psoriasis, inflammatory bowel disease, T cell-mediated dermatitis, stromal keratitis, uveitis, thyroiditis, sialitis and type I diabetes.
    Type: Grant
    Filed: May 20, 2004
    Date of Patent: January 19, 2010
    Assignee: Pharmaxis Pty Limited
    Inventors: William Butler Cowden, Gavin James Bartell, Bart Michael Eschler, Darren Ray March, Alan Robertson
  • Compounds and methods
    Patent number: 6878690
    Abstract: The present invention provides phosphotetrahydropyran compounds and the use thereof in treating diseases or conditions that are dependent on T-lymphocyte migration, as well as compositions containing said compounds.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: April 12, 2005
    Assignee: PharmAxis Pty Ltd.
    Inventors: William Butler Cowden, Bart Michael Eschler, Darren Ray March, Douglas John Francis, Sendaba Gerba, Gavin James Bartell, Brett Charlton
  • Novel compounds and methods
    Publication number: 20030176363
    Abstract: The present invention provides phosphotetrahydropyran compounds and the use thereof in treating diseases or conditions that are dependent on T-lymphocyte migration, as well as compositions containing said compounds.
    Type: Application
    Filed: January 9, 2003
    Publication date: September 18, 2003
    Applicant: PharmAxis Pty Ltd.
    Inventors: William Butler Cowden, Bart Michael Eschler, Darren Ray March, Douglas John Francis, Sendaba Gerba, Gavin James Bartell, Brett Charlton