Patents by Inventor Bart O. Roep

Bart O. Roep has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190315827
    Abstract: The present invention provides compositions and methods for treating insulin-dependent diabetes mellitus in a subject comprising administration of a self-vector encoding and expressing human proinsulin.
    Type: Application
    Filed: November 21, 2018
    Publication date: October 17, 2019
    Applicant: Tolerion, Inc.
    Inventors: Bart O. Roep, William H. Robinson, Paul Utz, Hideki Garren, Lawrence Steinman
  • Publication number: 20160068585
    Abstract: The present invention provides compositions and methods for treating insulin-dependent diabetes mellitus in a subject comprising administration of a self-vector encoding and expressing human proinsulin.
    Type: Application
    Filed: May 1, 2014
    Publication date: March 10, 2016
    Inventors: Bart O. Roep, William H. Robinson, Paul Utz, Hideki Garren, Lawrence Steinman
  • Patent number: 6040134
    Abstract: The present invention relates to a method of diagnosing preclinical insulin-dependent diabetes mellitus by determining the T cell response to a specific islet cell antigen fetal antigen 1 (FA1) or the presence of autoantibodies against FA1 in serum, a test kit for use in the method, as well as a pharmaceutical composition of FA1 and a method for use of the pharmaceutical composition for therapy of insulin-dependent diabetes mellitus.
    Type: Grant
    Filed: July 15, 1997
    Date of Patent: March 21, 2000
    Assignee: Novo Nordisk A/S
    Inventors: Ole Dragsbaek Madsen, Birgitte Koch Michelsen, Jacob Steen Petersen, Bart O. Roep, Borge Teisner