Patents by Inventor Bart O. Williams

Bart O. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low-density lipoprotein receptor 6 (LRP6) as a mammary stem cell marker and related methods
    Patent number: 7622267
    Abstract: A method for enriching a population of somatic mammary stem cells or mammary tumor stem cells based on low-density lipoprotein receptor-related protein 6 (LRP6). Also included are methods for screening for LRP6 modulators, as well as methods for reducing Wnt signaling, for treating Wnt signaling-related diseases, for detecting mammary basal-like cells, for diagnosing basal-like breast cancer, and for inhibiting proliferation of a tumor expressing LRP6, and compositions thereof.
    Type: Grant
    Filed: May 30, 2007
    Date of Patent: November 24, 2009
    Assignee: Van Andel Research Institute
    Inventors: Bart O. Williams, Charlotta Lindvall