Patents by Inventor Bart TEGENBOS

Bart TEGENBOS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC PRIMERS AND RELATED METHODS
    Publication number: 20230212559
    Abstract: The present disclosure provides chimeric primers suitable for use in the amplification of a nucleic acid sequence. In some aspects, these chimeric primers reduce the formation of primer dimers and/or off-target amplification products, compared to amplification reactions carried out using unmodified primers.
    Type: Application
    Filed: December 30, 2020
    Publication date: July 6, 2023
    Inventors: Jurgen DEL FAVERO, Lien HEYRMAN, Dirk GOOSSENS, Bart TEGENBOS
  • Modified multiplex and multistep amplification reactions and reagents therefor
    Patent number: 11578357
    Abstract: The invention relates to reagents and methods for improving the efficiency of multiplex nucleic acid amplification, in particular where overlapping amplicons are to be generated. The invention also relates to reagents and methods for improving the efficiency of multistep nucleic acid amplification, in particular the performance of two separate amplification reactions designed to occur in sequence in the same reaction mixture or vessel. The invention further relates to reagents and methods for improving multistep nucleic acid amplification reactions by controlling the output of the first amplification reaction. In particular, primers are provided that minimise the formation of aberrant amplification products. Such primers are particularly useful where first and second amplification reactions take place in a single reaction mixture or vessel.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: February 14, 2023
    Assignee: AGILENT TECHNOLOGIES, INC.
    Inventors: Jurgen Peter Lode Del Favero, Lien Heyrman, Bart Tegenbos, Dirk Goossens, Joachim De Schrijver
  • MODIFIED MULTIPLEX AND MULTISTEP AMPLIFICATION REACTIONS AND REAGENTS THEREFOR
    Publication number: 20200024651
    Abstract: The invention relates to reagents and methods for improving the efficiency of multiplex nucleic acid amplification, in particular where overlapping amplicons are to be generated. The invention also relates to reagents and methods for improving the efficiency of multistep nucleic acid amplification, in particular the performance of two separate amplification reactions designed to occur in sequence in the same reaction mixture or vessel. The invention further relates to reagents and methods for improving multistep nucleic acid amplification reactions by controlling the output of the first amplification reaction. In particular, primers are provided that minimise the formation of aberrant amplification products. Such primers are particularly useful where first and second amplification reactions take place in a single reaction mixture or vessel.
    Type: Application
    Filed: November 15, 2017
    Publication date: January 23, 2020
    Inventors: Jurgen Peter Lode DEL FAVERO, Lien HEYRMAN, Bart TEGENBOS, Dirk GOOSSENS, Joachim DE SHRIJVER