Patents by Inventor Bartholomaus Pieber

Bartholomaus Pieber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modular continuous flow device
    Patent number: 11731101
    Abstract: The invention refers to a modular continuous flow device for automated chemical multistep synthesis under continuous flow conditions. The device comprises a plurality of different types of continuous flow modules and a valve assembly for connecting the continuous flow modules to each other in a parallel or radial manner. This arrangement allows conducting chemical reaction sequences by pre-synthesizing and intermediately storing or simultaneously synthesizing at least one intermediate product which is needed in the main synthetic reaction sequence in order to obtain the final product.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: August 22, 2023
    Assignee: MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V.
    Inventors: Kerry Gilmore, Peter H. Seeberger, Bartholomaus Pieber, Sourav Chatterjee
  • MODULAR CONTINOUS FLOW DEVICE
    Publication number: 20210187468
    Abstract: The invention refers to a modular continuous flow device for automated chemical multistep synthesis under continuous flow conditions. The device comprises a plurality of different types of continuous flow modules and a valve assembly for connecting the continuous flow modules to each other in a parallel or radial manner. This arrangement allows conducting chemical reaction sequences by pre-synthesizing and intermediately storing or simultaneously synthesizing at least one intermediate product which is needed in the main synthetic reaction sequence in order to obtain the final product.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 24, 2021
    Inventors: Kerry Gilmore, Peter H. Seeberger, Bartholomaus Pieber, Sourav Chatterjee
  • Selective reduction of morphinan alkaloids
    Patent number: 10155771
    Abstract: The present disclosure relates to selective reduction of morphinan alkaloids in a continuous flow system. In particular, the present disclosure relates to selective reduction of thebaine or oripavine using hydrazine or a hydrazine-containing compound in a continuous flow system under elevated temperature and pressure condition to form 8,14-dihydrothebaine or 8,14-dihydrooripavine, respectively.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 18, 2018
    Assignee: Noramco, Inc.
    Inventors: D. Phillip Cox, C. Oliver Kappe, Bartholomaus Pieber
  • SELECTIVE REDUCTION OF MORPHINAN ALKALOIDS
    Publication number: 20170137432
    Abstract: The present disclosure relates to selective reduction of morphinan alkaloids in a continuous flow system. In particular, the present disclosure relates to selective reduction of thebaine or oripavine using hydrazine or a hydrazine-containing compound in a continuous flow system under elevated temperature and pressure condition to form 8,14-dihydrothebaine or 8,14-dihydrooripavine, respectively.
    Type: Application
    Filed: November 4, 2016
    Publication date: May 18, 2017
    Applicant: Noramco Inc.
    Inventors: D. Phillip Cox, C. Oliver Kappe, Bartholomaus Pieber