Patents by Inventor Bartholomeus Leonardus Haagmans

Bartholomeus Leonardus Haagmans has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral Compounds for Use in the Treatment of Coronavirus Infection
    Publication number: 20230192634
    Abstract: The invention provides a BAF complex modulating compound for use as a coronavirus antiviral; wherein the BAF complex modulating compound is of Formula (I):
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Inventors: Emily Carla Dykhuizen, Mart Matthias Lamers, Bartholomeus Leonardus Haagmans, Tokameh Mahmoudi
  • Human Betacoronavirus Lineage C and Identification of N-Terminal Dipeptidyl Peptidase As Its Virus Receptor
    Publication number: 20210246431
    Abstract: The invention provides an isolated essentially mammalian positive-sense single stranded RNA virus classifiable as belonging to the Order: Nidovirales; Family: Coronaviridae; Subfamily: Coronavirinae; Genus: Betacoronavirus; and non-Lineage A, non-Lineage B or non-Lineage D, human betacoronavirus. The invention also provides a human virus having a receptor binding domain (RBD) capable of binding to a dipeptidyl peptidase 4. The invention also provides diagnostic means and methods, prophylactic means and methods and therapeutic means and methods to be employed in the diagnosis, prevention and/or treatment of disease, in particular of respiratory disease, in particular of mammals, more in particular in humans.
    Type: Application
    Filed: September 21, 2020
    Publication date: August 12, 2021
    Inventors: Bartholomeus Leonardus Haagmans, Theodorus Marinus Bestebroer, Sander van Boheemen, Ronaldus Adrianus Maria Fouchier, Albertus Dominicus Marcellinus Erasmus Osterhaus, Ali Moh Zaki, Victor Stalin Raj, Berend Jan Bosch
  • Human Betacoronavirus lineage C and identification of N-terminal dipeptidyl peptidase as its virus receptor
    Patent number: 10781426
    Abstract: The invention provides an isolated essentially mammalian positive-sense single stranded RNA virus classifiable as belonging to the Order: Nidovirales; Family: Coronaviridae; Subfamily: Coronavirinae; Genus: Betacoronavirus; and non-Lineage A, non-Lineage B or non-Lineage D, human betacoronavirus. The invention also provides a human virus having a receptor binding domain (RBD) capable of binding to a dipeptidyl peptidase 4. The invention also provides diagnostic means and methods, prophylactic means and methods and therapeutic means and methods to be employed in the diagnosis, prevention and/or treatment of disease, in particular of respiratory disease, in particular of mammals, more in particular in humans.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: September 22, 2020
    Assignees: Erasmus University Medical Center Rotterdam, Dr. Soliman Fakeeh Hospital
    Inventors: Bartholomeus Leonardus Haagmans, Theodorus Marinus Bestebroer, Sander van Boheemen, Ronaldus Adrianus Maria Fouchier, Albertus Dominicus Marcellinus Erasmus Osterhaus, Ali Moh Zaki, Victor Stalin Raj, Berend Jan Bosch
  • Human Betacoronavirus Lineage C and Identification of N-Terminal Dipeptidyl Peptidase As Its Virus Receptor
    Publication number: 20150275183
    Abstract: The invention provides an isolated essentially mammalian positive-sense single stranded RNA virus classifiable as belonging to the Order: Nidovirales; Family: Coronaviridae; Subfamily: Coronavirinae; Genus: Betacoronavirus; and non-Lineage A, non-Lineage B or non-Lineage D, human betacoronavirus. The invention also provides a human virus having a receptor binding domain (RBD) capable of binding to a dipeptidyl peptidase 4. The invention also provides diagnostic means and methods, prophylactic means and methods and therapeutic means and methods to be employed in the diagnosis, prevention and/or treatment of disease, in particular of respiratory disease, in particular of mammals, more in particular in humans.
    Type: Application
    Filed: September 23, 2013
    Publication date: October 1, 2015
    Inventors: Bartholomeus Leonardus Haagmans, Theodorus Marinus Bestebroer, Sander van Boheemen, Ronaldus Adrianus Maria Fouchier, Albertus Dominicus Marcellinus Erasmus Osterhaus, Ali Moh Zaki, Victor Stalin Raj, Berend Jan Bosch