Patents by Inventor Baruch B. Lieber

Baruch B. Lieber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210043113
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves, which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart.
    Type: Application
    Filed: August 10, 2020
    Publication date: February 11, 2021
    Inventors: Chandramouli Sadasivan, Baruch B. Lieber, Brandon Joseph Kovarovic, Louis E. Abejar, Henry Woo, MD, David Jeffrey Carson, David Fiorella, Michael Romeo, Gary Bunch, Karl Keppeler
  • Publication number: 20200160753
    Abstract: A device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves, which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters, such as flow rates, fluidic pressure, and heart rate, may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system to simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.
    Type: Application
    Filed: September 20, 2019
    Publication date: May 21, 2020
    Inventors: Chandramouli Sadasivan, Baruch B. Lieber, Brandon Joseph Kovarovic, Louis E. Abejar, Henry Woo, David Jeffrey Carson, David Fiorella, Michael Romeo, Gary Bunch, Karl Keppeler
  • Publication number: 20190206283
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters such as flow rates, fluidic pressure, and heart rate may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system to simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.
    Type: Application
    Filed: March 8, 2019
    Publication date: July 4, 2019
    Inventors: David Jeffrey Carson, Baruch B. Lieber, Chandramouli Sadasivan, David Fiorella, Henry Woo, Michael Romeo, Gary Bunch
  • Patent number: 10229615
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters such as flow rates, fluidic pressure, and heart rate may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: March 12, 2019
    Assignee: Vascular Simulations Inc.
    Inventors: David Jeffrey Carson, Baruch B. Lieber, Chandramouli Sadasivan, David Fiorella, Henry Woo, Michael Romeo, Gary Bunch, Karl Keppeler
  • Publication number: 20180333588
    Abstract: In some embodiments, an apparatus includes a catheter having a catheter body, a light emitter disposed at a distal end of the catheter body, and a fluid conduit coupleable to a source of fluid. The fluid conduit configured to discharge fluid from the source via the conduit and out a distal end of the catheter body. A spacing member is disposed at the distal end of the catheter body and can be moved between a collapsed configuration and an expanded configuration. In the expanded configuration, the spacing member is disposed about the light emitter. The spacing member is at least partially transmissive and/or transflective of light emitted from the light emitter. The apparatus configured to be inserted at least partially into a body lumen, to discharge fluid into the body lumen, and to emit light from the light emitter to illuminate an interior wall of the body lumen.
    Type: Application
    Filed: May 10, 2018
    Publication date: November 22, 2018
    Applicant: Illumnation Corp.
    Inventors: Baruch B. LIEBER, John A. ROSE
  • Publication number: 20160027345
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiovascular functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic valves which simulate mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a control unit and sensors, one or more parameters such as flow rates, fluidic pressure, and heart rate may be automatically controlled, using feedback loop mechanisms to adjust parameters of the hydraulic system simulate a wide variety of cardiovascular conditions including normal heart function, severely diseased or injured heart conditions, and compressed vasculature, such as hardening of the arteries.
    Type: Application
    Filed: July 31, 2015
    Publication date: January 28, 2016
    Inventors: David Jeffrey Carson, Baruch B. Lieber, Chandramouli Sadasivan, David Fiorella, Henry Woo, MD, Michael Romeo, Gary Bunch, Karl Keppeler
  • Patent number: 9183763
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiac functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a remote handheld electronic controller and manual adjustments from a main control panel, the air pressure level, fluidic pressure, and heart rate is controlled to induce contractions that simulate a wide variety of heart conditions ranging from normal heart function to severely diseased or injured heart conditions.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: November 10, 2015
    Assignee: Vascular Simulations, LLC
    Inventors: David Jeffrey Carson, Baruch B. Lieber, Chandramouli Sadasivan, David John Florella, Henry Heesang Woo, Michael Romeo
  • Publication number: 20130196301
    Abstract: The present invention describes a device and system for simulating normal and disease state cardiac functioning, including an anatomically accurate left cardiac simulator for training and medical device testing. The system and device uses pneumatically pressurized chambers to generate ventricle and atrium contractions. In conjunction with the interaction of synthetic mitral and aortic valves, the system is designed to generate pumping action that produces accurate volume fractions and pressure gradients of pulsatile flow, duplicating that of a human heart. Through the use of a remote handheld electronic controller and manual adjustments from a main control panel, the air pressure level, fluidic pressure, and heart rate is controlled to induce contractions that simulate a wide variety of heart conditions ranging from normal heart function to severely diseased or injured heart conditions.
    Type: Application
    Filed: January 31, 2012
    Publication date: August 1, 2013
    Inventors: David Jeffrey Carson, Baruch B. Lieber, Chanderamouli Sadasivan, David Fiorella, Henry Woo, Michael Romao
  • Patent number: 8419787
    Abstract: A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.
    Type: Grant
    Filed: February 21, 2010
    Date of Patent: April 16, 2013
    Assignee: Surpass Medical Ltd
    Inventors: Ofer Yodfat, Baruch B. Lieber, Ygael Grad, Boaz Nishri
  • Publication number: 20120071911
    Abstract: A method and device for occluding an aneurysm. The device may include a wire having a shape memory. The wire may define a coil. The wire may further define a first substantially spherical helix and a second substantially spherical helix nested within the first substantially spherical helix. A catheter may be included, being releaseably engageable to the wire, the wire being at least partially disposed within the catheter.
    Type: Application
    Filed: May 20, 2009
    Publication date: March 22, 2012
    Applicant: UNIVERSITY OF MIAMI
    Inventors: Chandramouli Sadasivan, Baruch B Lieber
  • Patent number: 7942925
    Abstract: A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: May 17, 2011
    Assignee: Surpass Medical Ltd.
    Inventors: Ofer Yodfat, Baruch B. Lieber, Ygael Grad, Boaz Nishri
  • Publication number: 20100198334
    Abstract: A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.
    Type: Application
    Filed: February 21, 2010
    Publication date: August 5, 2010
    Applicant: Surpass Medical Ltd.
    Inventors: Ofer Yodfat, Baruch B. Lieber, Ygael Grad, Boaz Nishri
  • Publication number: 20090270970
    Abstract: A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.
    Type: Application
    Filed: July 2, 2009
    Publication date: October 29, 2009
    Applicant: Surpass Medical Ltd.
    Inventors: Ofer YODFAT, Baruch B. Lieber, Ygael Grad, Boaz Nishri
  • Patent number: 7572290
    Abstract: A method and apparatus for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exhibiting a porosity index pre-selected to skew blood flow about the bifurcation away from the aneurysm; inserting the first mesh-like tube into the source blood vessel and the first branch vessel; and securing the first mesh-like tube to at least one of the source blood vessel and the first branch vessel, whereby blood flowing from the source blood vessel flows without undue impedance to the first branch vessel and the second branch vessel while being skewed away from the aneurysm.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: August 11, 2009
    Assignee: Surpass Medical Ltd.
    Inventors: Ofer Yodfat, Baruch B. Lieber, Ygael Grad, Boaz Nishri
  • Patent number: 6686203
    Abstract: A histological staining technique that allows quantification of previously unmeasured parameters involved in surgical arteriovenous malformation (AVM) embolization. The invention allows the evaluation of the polymerization characteristics of various ratios of embolization agents, such as Lipiodol/n-butyl 2-cyanoacrylate (NBCA)/glacial acetic acid (GAA) mixtures, by virtue of a new tissue sample preparation protocol and staining technique. To determine the depth of NBCA penetration within the AVM model and to characterize the polymerization patterns of various mixtures within a model vessel, histologic cross-and longitudinal sections were prepared for microscopy using a new staining method including the use of europium aryl-&bgr;-diketone complex and petroleum ether. Paraffin-embedded tissue sections were subjected to the staining protocol to improve differentiation between NBCA and Lipiodol.
    Type: Grant
    Filed: September 11, 2001
    Date of Patent: February 3, 2004
    Inventors: William J. Calvo, Baruch B. Lieber
  • Publication number: 20030109917
    Abstract: The present invention relates to a stent including a variable porosity, tubular structure having pores defined by structural surfaces. The tubular structure has a low porosity region on a path around the tubular structure, where the low porosity region is less porous than other regions located on the path and fully or partially obstructs passage of fluid. The low porosity region is larger than the structural surfaces between adjacent pores. Also disclosed is a method of altering blood flow within and near an opening of a defective blood vessel involving deploying the above stent of the present invention in a defective blood vessel so that the low porosity region is aligned to and in contact with an opening in the defective blood vessel, thereby altering blood flow within and near the opening of the defective blood vessel.
    Type: Application
    Filed: July 18, 2002
    Publication date: June 12, 2003
    Inventors: Stephen Rudin, Baruch B. Lieber, Matthew J. Gounis
  • Publication number: 20020031443
    Abstract: A histological staining technique that allows quantification of previously unmeasured parameters involved in surgical AVM embolization. The invention allows the evaluation of the polymerization characteristics of various ratios of embolization agents, such as Lipiodol/NBCA/glacial acetic acid (GAA) mixtures, by virtue of a new tissue sample preparation protocol and staining technique.
    Type: Application
    Filed: September 11, 2001
    Publication date: March 14, 2002
    Inventors: William J. Calvo, Baruch B. Lieber
  • Publication number: 20020025267
    Abstract: A micro-injection pump for angiography and micro-intervention procedures comprises first and second linear traverses each have a pusher element movable by stepper motor drive for controlling discharge from a respective micro-syringe engaged by the pusher element. The first micro-syringe preferably contains a volume of a soluble contrast medium, and the second micro-syringe preferably contains a volume of an insoluble contrast medium. Fluid discharged by the micro-syringes is directed to a bifurcated micro-droplet generator having a straight primary passage and an obliquely merging tributary passage. Insoluble contrast medium from the second micro-syringe flows through a micro-sized injection needle extending partially and coaxially within the primary passage to a termination point just downstream from where the tributary passage joins the primary passage.
    Type: Application
    Filed: June 20, 2001
    Publication date: February 28, 2002
    Inventors: Baruch B. Lieber, Ajay K. Wakhloo, Stephen Rudin, Joseph A. Wodenscheck
  • Patent number: 6285739
    Abstract: A radiographic imaging apparatus and method for vascular interventions for acquiring very high resolution radiographic images over a small region of interest (ROI). The apparatus and associated method employs digital solid state x-ray image detectors for the medical imaging application of angiography. A mechanical arrangement, for example an arm attached to an existing large area x-ray detector, allows the small area ROI digital detector to be temporarily positioned over a region located by the standard large area imager so that additional very high resolution digital images may be obtained over the ROI.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: September 4, 2001
    Assignee: The Research Foundation of State University of New York
    Inventors: Stephen Rudin, Daniel R. Bednarek, Baruch B. Lieber, Ajay Kumar Wakhloo