Patents by Inventor Baruch S. Blumberg

Baruch S. Blumberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of membrane-associated viral replication
    Patent number: 6465487
    Abstract: Methods for inhibiting morphogenesis of host cell membrane-budding viruses and infections caused thereby using compounds that inhibit host cell glucosidase or glucosyltransferase enzymes. Methods for treating lipid storage diseases using compounds that inhibit glucosyl transferance enzymes.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: October 15, 2002
    Assignees: Synergy Pharmaceuticals, Inc., Thomas Jefferson University, The Chancellor, Masters and Scholars of the University of Oxford
    Inventors: Timothy M. Block, Raymond A. Dwek, Baruch S. Blumberg, Anand Mehta, Frances Platt, Terry D. Butters, Nicole Zitzmann
  • Method of inhibiting hepatitis B virus
    Patent number: 6037351
    Abstract: A method is disclosed for the treatment of hepatitis B virus (HBV) infections which comprises administering to the infected host an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which the alkyl group contains from 3 to 6 carbon atoms.
    Type: Grant
    Filed: July 11, 1996
    Date of Patent: March 14, 2000
    Assignee: G. D. Searle & Co.
    Inventors: Timothy M. Block, Baruch S. Blumberg, Raymond A. Dwek
  • Method of treating retrovirus infection
    Patent number: 4937074
    Abstract: Method of treating retrovirus infection by administering extract of Phyllanthus niruri.
    Type: Grant
    Filed: March 29, 1988
    Date of Patent: June 26, 1990
    Assignee: Fox Chase Cancer Center
    Inventors: Pinayur S. Venkateswaran, Irving Millman, Baruch S. Blumberg
  • Composition, pharmaceutical preparation and method for treating viral hepatitus
    Patent number: 4673575
    Abstract: A pharmaceutical preparation comprising the methanol extractable components of Phyllanthus niruri L. is administered to patients suffering from hepatitis B virus infection in an amount effective for inhibiting the growth of said virus.
    Type: Grant
    Filed: April 26, 1985
    Date of Patent: June 16, 1987
    Assignee: Fox Chase Cancer Center
    Inventors: Pinayur S. Venkateswaran, Irving Millman, Baruch S. Blumberg
  • Hepatitis B testing reagent and method
    Patent number: 4189464
    Abstract: A test reagent reagent for HB.sub.s A.sub.g is prepared by applying to a suitable substrate, such as a polystyrene bead, a first coat of purified HB.sub.s A.sub.g to an extent which will permit complete coverage by anti-HB.sub.s. After washing HB.sub.s A.sub.g coated substrate, serum containing anti-HB.sub.s, or an IgG fraction of serum containing anti-HB.sub.s, is applied as a second coat as a second coat in an amount which substantially completely occupies the reacting sites of the HB.sub.s A.sub.g on the outside of the substrate and leaves an excess of antibody reacting groups in a free state, and any unattached material is washed off.A test sample which is to be tested for HB.sub.s A.sub.g is then contacted with the reagent thus produced, permitting attachment of HB.sub.s A.sub.g if present, and washing is done.Then a source of anti-HB.sub.s, such as an IgG fraction containing anti-HB.sub.
    Type: Grant
    Filed: May 5, 1978
    Date of Patent: February 19, 1980
    Assignee: Institute for Cancer Research
    Inventors: Baruch S. Blumberg, Irving Millman