Patents by Inventor Baskar Nammalwar

Baskar Nammalwar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240166609
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. The subject compounds and compositions are useful for the treatment of bacterial infections, such as pneumonia.
    Type: Application
    Filed: February 8, 2022
    Publication date: May 23, 2024
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, David T. PUERTA
  • Publication number: 20240150298
    Abstract: Provided herein are heterocyclic compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. The subject compounds and compositions are useful for the treatment of bacterial infections, such as pneumonia.
    Type: Application
    Filed: February 8, 2022
    Publication date: May 9, 2024
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, David T. PUERTA
  • Publication number: 20240002373
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: June 27, 2023
    Publication date: January 4, 2024
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • Publication number: 20230382891
    Abstract: Described herein are compounds that are glutaminyl-peptide cyclotransferase like (QPCTL) protein modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of QPCTL activity.
    Type: Application
    Filed: October 19, 2021
    Publication date: November 30, 2023
    Inventors: Min TENG, David T. PUERTA, Baskar NAMMALWAR, Christian PEREZ, David LONERGAN, David Pifer MARTIN
  • Patent number: 11731962
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: August 22, 2023
    Assignee: BLACKSMITH MEDICINES, INC.
    Inventors: Min Teng, Baskar Nammalwar, David T. Puerta
  • Publication number: 20230201214
    Abstract: Provided herein is an LpxC inhibitor compound, as well as pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: February 23, 2023
    Publication date: June 29, 2023
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • Publication number: 20220324846
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: June 9, 2022
    Publication date: October 13, 2022
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
  • Patent number: 11407740
    Abstract: Provided herein are heterocyclic derivative compounds of Formula (II), and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: August 9, 2022
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Xiaoming Li, Christian Perez, Ian Yule, Adele Faulkner, Holly Atton, Alastair Parkes, Serge Convers-Reignier, Michelle Southey, David T. Puerta
  • Publication number: 20220117937
    Abstract: The present invention discloses methods of inhibiting biofilm formation, increasing bacteriocidal activity within a biofilm, treating bacteria within a biofilm, or remediating a biofilm in or on a subject, comprising administering to the subject an effective amount of a compound according to Formula I: wherein R1-5 are defined herein.
    Type: Application
    Filed: October 15, 2021
    Publication date: April 21, 2022
    Applicants: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College, University of Kansas, Oklahoma State University
    Inventors: Mario Rivera, Huili Yao, Richard A. Bunce, Baskar Nammalwar, Krishna Kumar Gnanasekaran, Kate Eshelman, Achala N.D. Punchi Hewage, Scott Lovell, Anabel Soldano
  • Publication number: 20220081421
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: November 14, 2019
    Publication date: March 17, 2022
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Ian YULE, Alastair PARKES, Heather TYE, Holly ATTON, Helen WILLIAMS, Adele FAULKNER, Serge CONVERS-REIGNIER, David T. PUERTA
  • Publication number: 20220031661
    Abstract: The present technology provides compounds of Formula I and related methods for treating a bacterial infection as well as methods for inhibiting interaction of a bacterioferritin and a bacterioferritin-associated ferredoxin.
    Type: Application
    Filed: December 3, 2019
    Publication date: February 3, 2022
    Inventors: Mario RIVERA, Huili YAO, Richard A. BUNCE, Baskar NAMMALWAR, Krishna Kumar GNANASEKARAN, Kate ESHELMAN, Achala N.D. PUNCHI HEWAGE, Scott LOVELL
  • Publication number: 20210315902
    Abstract: Provided herein is an LpxC inhibitor compound, as well as pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 14, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • Publication number: 20210309651
    Abstract: Provided herein is an LpxC inhibitor compound, as well as methods of making and pharmaceutical compositions comprising said compound, and methods of use thereof in the treatment of disease that would benefit from treatment with an LpxC inhibitor, including gram-negative bacterial infections such as urinary tract infections and the like.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 7, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, David T. PUERTA
  • Publication number: 20210221796
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: March 18, 2021
    Publication date: July 22, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, Xiaoming LI, Christian PEREZ, Ian YULE, Adele FAULKNER, Holly ATTON, Alastair PARKES, Serge CONVERS-REIGNIER, Michelle SOUTHEY, David T. PUERTA
  • Patent number: 11021471
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: June 1, 2021
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, Xiaoming Li, David T. Puerta
  • Publication number: 20210078957
    Abstract: The present teachings relate to hydroxypyridinone and hydroxypyrimidinone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Application
    Filed: November 24, 2020
    Publication date: March 18, 2021
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, David T. PUERTA
  • Patent number: 10875832
    Abstract: The present teachings relate to hydroxypyrimidinone derivatives of Formula II, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Grant
    Filed: July 15, 2019
    Date of Patent: December 29, 2020
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
  • Publication number: 20200255413
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: May 9, 2018
    Publication date: August 13, 2020
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, Xiaoming LI, David T. PUERTA
  • Patent number: 10611747
    Abstract: The present teachings relate to pyrone derivatives, pharmaceutical compositions thereof, and methods of using such compounds to treat bacterial infections.
    Type: Grant
    Filed: November 9, 2016
    Date of Patent: April 7, 2020
    Assignee: FORGE THERAPEUTICS, INC.
    Inventors: Min Teng, Baskar Nammalwar, Konstantin Taganov, David T. Puerta
  • Publication number: 20200095236
    Abstract: Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.
    Type: Application
    Filed: May 9, 2018
    Publication date: March 26, 2020
    Inventors: Min TENG, Baskar NAMMALWAR, Konstantin TAGANOV, Xiaoming LI, David T. PUERTA, Serge CONVERS-REIGNIER, Holly ATTON, Ian YULE, Heather TYE, Adele FAULKNER, Alastair PARKES