Patents by Inventor Bason E. Clancy

Bason E. Clancy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPORE-BASED NUCLEIC ACID ANALYSIS WITH MIXED FRET DETECTION
    Publication number: 20210130887
    Abstract: Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences of nucleic acids, are provided herein. In certain variations, methods and systems for determining a nucleotide sequence of a polynucleotide, which include measuring mixed FRET signals as a polynucleotide translocates through a nanopore and determining a nucleotide sequence of the polynucleotide from the mixed FRET signals, are provided.
    Type: Application
    Filed: August 6, 2020
    Publication date: May 6, 2021
    Applicant: Quantapore, Inc.
    Inventors: Martin HUBER, Bason E. CLANCY, Paul HARDENBOL
  • NANOPORE-BASED NUCLEIC ACID ANALYSIS WITH MIXED FRET DETECTION
    Publication number: 20190360035
    Abstract: Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences of nucleic acids, are provided herein. In certain variations, methods and systems for determining a nucleotide sequence of a polynucleotide, which include measuring mixed FRET signals as a polynucleotide translocates through a nanopore and determining a nucleotide sequence of the polynucleotide from the mixed FRET signals, are provided.
    Type: Application
    Filed: May 24, 2019
    Publication date: November 28, 2019
    Applicant: Quantapore, Inc.
    Inventors: Martin HUBER, Bason E. CLANCY, Paul HARDENBOL
  • NANOPORE-BASED NUCLEIC ACID ANALYSIS WITH MIXED FRET DETECTION
    Publication number: 20180073072
    Abstract: Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences of nucleic acids, are provided herein. In certain variations, methods and systems for determining a nucleotide sequence of a polynucleotide, which include measuring mixed FRET signals as a polynucleotide translocates through a nanopore and determining a nucleotide sequence of the polynucleotide from the mixed FRET signals, are provided.
    Type: Application
    Filed: November 28, 2017
    Publication date: March 15, 2018
    Applicant: Quantapore, Inc.
    Inventors: Martin HUBER, Bason E. CLANCY, Paul HARDENBOL
  • Nanopore-based nucleic acid analysis with mixed FRET detection
    Patent number: 9862997
    Abstract: Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences of nucleic acids, are provided herein. In certain variations, methods and systems for determining a nucleotide sequence of a polynucleotide, which include measuring mixed FRET signals as a polynucleotide translocates through a nanopore and determining a nucleotide sequence of the polynucleotide from the mixed FRET signals, are provided.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: January 9, 2018
    Assignee: Quantapore, Inc.
    Inventors: Martin Huber, Bason E. Clancy, Paul Hardenbol
  • Reducing background fluorescence in MEMS materials by low energy ion beam treatment
    Patent number: 9651539
    Abstract: Methods for fabricating materials useful for optical detection in microfluidic and nanofluidic devices, such as those used in nanopore-based nucleic acid sequencing are described herein. In certain variations, a method of reducing background fluorescence in a MEMS material may include the step of treating a surface of the MEMS material with a low energy ion beam.
    Type: Grant
    Filed: March 16, 2015
    Date of Patent: May 16, 2017
    Assignee: Quantapore, Inc.
    Inventors: Martin Huber, Bason E. Clancy, Adam R. Hall
  • REDUCING BACKGROUND FLUORESCENCE IN MEMS MATERIALS BY LOW ENERGY ION BEAM TREATMENT
    Publication number: 20160077078
    Abstract: Methods for fabricating materials useful for optical detection in microfluidic and nanofluidic devices, such as those used in nanopore-based nucleic acid sequencing are described herein. In certain variations, a method of reducing background fluorescence in a MEMS material may include the step of treating a surface of the MEMS material with a low energy ion beam.
    Type: Application
    Filed: March 16, 2015
    Publication date: March 17, 2016
    Applicant: Quantapore, Inc.
    Inventors: Martin HUBER, Bason E. CLANCY, Adam R. HALL
  • NANOPORE-BASED NUCLEIC ACID ANALYSIS WITH MIXED FRET DETECTION
    Publication number: 20160076091
    Abstract: Various methods, systems and devices for optical detection and analysis of polymers, such as polynucleotides, using nanopores, e.g., for determining sequences of nucleic acids, are provided herein. In certain variations, methods and systems for determining a nucleotide sequence of a polynucleotide, which include measuring mixed FRET signals as a polynucleotide translocates through a nanopore and determining a nucleotide sequence of the polynucleotide from the mixed FRET signals, are provided.
    Type: Application
    Filed: May 23, 2014
    Publication date: March 17, 2016
    Applicant: Quantapore, Inc.
    Inventors: Martin HUBER, Bason E. CLANCY, Paul HARDENBOL
  • HYBRID NANOPORE DEVICE WITH OPTICAL DETECTION AND METHODS OF USING SAME
    Publication number: 20140335513
    Abstract: The invention is directed to a device comprising a protein nanopore immobilized in a lipid layer within an aperture of a solid phase substrate, which provides a stable platform for using first and second members of one or more FRET pairs to generate optical signals as a labeled analyte translocates through the bore of the protein nanopore. In another aspect, the invention is directed to the use of the device to determine the nucleotide sequence of a polynucleotide analyte.
    Type: Application
    Filed: October 28, 2012
    Publication date: November 13, 2014
    Applicant: QUANTAPORE, INC.
    Inventors: Martin Huber, Bason E. Clancy