Patents by Inventor Bayer HealthCare, LLC
Bayer HealthCare, LLC has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130344585Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.Type: ApplicationFiled: March 12, 2013Publication date: December 26, 2013Applicant: BAYER HEALTHCARE LLCInventor: BAYER HEALTHCARE LLC
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Publication number: 20130345402Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.Type: ApplicationFiled: March 12, 2013Publication date: December 26, 2013Applicant: Bayer Healthcare LLCInventor: Bayer Healthcare LLC
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Publication number: 20130225809Abstract: This invention relates to pyrrozolotriazine compounds, pharmaceutical compositions containing such compounds and the use of those compounds and compositions for the prevention and/or treatment of hyper-proliferative disorders and diseases associated with angiogenesis.Type: ApplicationFiled: December 20, 2012Publication date: August 29, 2013Applicant: Bayer HealthCare LLCInventor: Bayer HealthCare LLC
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Publication number: 20130188302Abstract: A device for managing health data provides a first housing portion including a data storage system that stores health data and a second housing portion including a data communications element. The data communications element provides data communications between the data storage system and a processing device that processes the health data according to a data-management software. The first housing portion and the second housing portion are connected by a cable that communicates signals between the data communications element and other components in the first housing portion. Another device for managing health data provides a first housing portion including a health data management system and a data communications element that provides data communications between the health data management system and an external processing device. The second housing portion is removably coupled to the first housing portion, and includes at least one component used by the health data management system.Type: ApplicationFiled: March 9, 2013Publication date: July 25, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer HealthCare LLC
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Publication number: 20130183699Abstract: Glucose measured in blood samples is distinguished from glucose measured in the control solutions used to test the optical instruments which make such measurements. The control solutions contain a labeling substance recognized by the optical instrument to distinguish glucose measurements made of control solutions from those made of blood samples.Type: ApplicationFiled: March 6, 2013Publication date: July 18, 2013Applicant: Bayer HealthCare, LLCInventor: Bayer HealthCare, LLC
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Publication number: 20130171028Abstract: An analyte meter for an analyte test strip includes a light source configured to emit a light having a wavelength substantially similar to the maximum absorption band of Hb, an optics assembly configured to direct the light emitted by the light source to a test strip, and a photodetector configured to quantitatively detect light emanating from the test strip and to generate a signal correlating to an analyte concentration in the test strip.Type: ApplicationFiled: December 28, 2012Publication date: July 4, 2013Applicant: BAYER HEALTHCARE LLCInventor: BAYER HEALTHCARE LLC
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Publication number: 20130168403Abstract: The present disclosure relates to packaging containers for holding a plurality of test sensors. The packaging container may include a first semi-circular housing and a second semi-circular housing. The first semi-circular housing has a plurality of first test sensor containing regions. Each of the plurality of the first test sensor containing regions is adapted to contain at least one test sensor having a top portion covered by a foil cover. The second semi-circular housing has a plurality of second test sensor containing regions. Each of the plurality of the second test sensor containing regions is adapted to contain at least one test sensor. The second semi-circular housing has a top portion. The first semi-circular housing and the second semi-circular housing are positioned adjacent to each other.Type: ApplicationFiled: December 28, 2012Publication date: July 4, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer HealthCare LLC
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Publication number: 20130161206Abstract: According to one embodiment of the present invention, an electrochemical sensor (10) for detecting the concentration of analyte in a fluid test sample is disclosed. The sensor (10) includes a counter electrode having a high-resistance portion for use in detecting whether a predetermined amount of sample has been received by the test sensor.Type: ApplicationFiled: February 25, 2013Publication date: June 27, 2013Applicant: Bayer HealthCare LLCInventor: Bayer HealthCare LLC
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Publication number: 20130126350Abstract: A method of forming a 3-phenylimino-3H-phenothiazine or a 3-phenylimino-3H-phenoxazine mediator includes providing a first reactant including phenothiazine or phenoxazine, providing a first solvent, providing a second reactant and providing a second solvent. The first reactant, first solvent, second reactant and second solvent are combined to form a reactants solution. Sodium persulfate is added to the reactants solution to couple the first and second reactants resulting in a reaction solution including the 3-phenylimino-3H-phenothiazine or the 3-phenylimino-3H-phenoxazine mediator.Type: ApplicationFiled: December 17, 2012Publication date: May 23, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer Healthcare LLC
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Publication number: 20130131122Abstract: A compound of Formula (I): salts thereof, prodrugs thereof, metabolites thereof, pharmaceutical compositions containing such a compound, and use of such compound and compositions to treat diseases mediated by raf, VEGFR, PDGFR, p38 and flt-3.Type: ApplicationFiled: November 5, 2012Publication date: May 23, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer Healthcare LLC
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Publication number: 20130098778Abstract: The present invention relates to improved electrochemical biosensor strips and methods for determining the concentration of an analyte in a sample. By selectively measuring a measurable species residing in a diffusion barrier layer, to the substantial exclusion of the measurable species residing exterior to the diffusion barrier layer, measurement errors introduced by sample constituents, such as red blood cells, and manufacturing variances may be reduced.Type: ApplicationFiled: November 6, 2012Publication date: April 25, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer HealthCare LLC
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Publication number: 20130078724Abstract: A method of distinguishing a control solution from a sample in an electrochemical test sensor is performed. The method includes adding a control marker to the control solution. The control solution includes the control marker and analyte. The test sensor includes working and counter electrodes, and a reagent. A potential is applied to the test sensor to oxidize the control marker and the analyte. The resulting electrical current is measured. A potential is applied to the test sensor lower than the other potential in which the potential is sufficient to oxidize the analyte and not the control marker. The resulting electrical current is measured. Determining whether a control solution or a sample is present based on the measured electrical currents. To increase the measured current, a salt may be added to the control solution in an amount sufficient to increase the electrical current by at least 5% as compared to a control solution in the absence of a salt.Type: ApplicationFiled: November 20, 2012Publication date: March 28, 2013Applicant: BAYER HEALTHCARE LLCInventor: Bayer HealthCare LLC
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Publication number: 20130061663Abstract: An assembly determines an analyte concentration in a sample of body fluid. The assembly includes a test sensor having a fluid-receiving area for receiving a sample of body fluid, where the fluid-receiving area contains a reagent that produces a measurable reaction with an analyte in the sample. The assembly also includes a meter having a port or opening configured to receive the test sensor; a measurement system configured to determine a measurement of the reaction between the reagent and the analyte; and a temperature-measuring system configured to determine a measurement of the test-sensor temperature when the test sensor is received into the opening. The meter determines a concentration of the analyte in the sample according to the measurement of the reaction and the measurement of the test-sensor temperature.Type: ApplicationFiled: November 5, 2012Publication date: March 14, 2013Applicant: BAYER HEALTHCARE LLCInventor: BAYER HEALTHCARE LLC
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Publication number: 20130044119Abstract: A device adapted to determine an analyte concentration of a fluid sample using a test sensor. The device comprises a display adapted to display information to a user. The device further comprises at least one user-interface mechanism adapted to allow the user to interact with the device. The device further comprises a body portion including at least one opening formed therein, the at least one opening being of sufficient size to receive the test sensor. The device further comprises a memory adapted to store a plurality of stored analyte concentrations. The device further comprises a processing feature adapted to inhibit the stored analyte concentrations from being displayed on the display.Type: ApplicationFiled: October 22, 2012Publication date: February 21, 2013Applicant: BAYER HEALTHCARE, LLCInventor: Bayer HealthCare, LLC