Abstract: The present invention relates to an inserter for an intrauterine system comprising a handle (3), and an insertion tube (6) having a first end and a second end, and being arranged in connection with the handle. The inserter is characterized in that the first end of the insertion tube (6) comprises at least one frame slot for receiving a frame of the intrauterine system. The invention also relates to a kit comprising an inserter according to the present invention and an intrauterine system, wherein the intrauterine system (1) comprises a therapeutic component (1b) and a continuous, closed frame (1a), the therapeutic component (1b) being connected to the frame (1a) at least one point, and therapeutic component (1b) of the intrauterine system (1) is at least mainly arranged inside the first end of the insertion tube (6) and the frame (1a) of the intrauterine system (1) is at least mainly arranged outside the first end of the insertion tube (6).

Abstract: The invention relates to a process for the preparation of isocyanates in a system network comprising an isocyanate production plant, a chlorine production plant and a phosgene production plant, in which carbon dioxide formed as a by-product is partially to completely condensed out with the gaseous chlorine formed in the chlorine production plant and enters into the phosgene preparation process and, after the preparation of phosgene, the predominant part of the carbon dioxide formed is thereby sluiced out of the system network in gaseous form.

Abstract: A herbicide combination comprising of components (A) and (B) exhibit synergistic herbicidal effects, where (A) is one or more herbicides selected from the group consisting of heteroaryloxy- and aryloxy-phenoxypropionic acids, their salts and esters and cyclohexanediones, and (B) is one or more herbicides selected from the group consisting of (B1) herbicides which are selective in rice, mainly against mono-cotyledonous plants, (B2) herbicides which are selective in rice, mainly against dicotyledonous harmful plants and cyperaceae, (B3) herbicides which are selective in rice, mainly against cyperaceae and (B4) herbicides which are selective in rice, mainly against mono-cotyledonous and dicotyledonous plants and cyperaceae.

Abstract: The present application relates to a novel and efficient process for preparing novel substituted 5-fluoro-1H-pyrazolopyridines of the formula (VI) which are suitable as an intermediate for production of medicaments and for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders. More particularly, the 5-fluoro-1H-pyrazolopyridines of the formula (VI) are suitable for preparation of the compound of the formula (I) which serves for production of medicaments, for production of medicaments for treatment and/or prophylaxis of cardiovascular disorders.

Abstract: Disclosed herein is a method of feeding carbon nano tubes (“CNTs”) to a fluid wherein the CNTs are provided in the form of a powder of tangled agglomerates of CNTs, the powder of tangled agglomerates is fed to a dosing chamber, a pressure pulse is applied to the dosing chamber to expel the CNTs from an outlet of the dosing chamber in such a way that the agglomerates are at least partially disintegrated by the pressure and accompanying shearing forces, and the CNTs are fed into said fluid to distribute the CNTs in the fluid and form a composite material.

Abstract: A herbicide combination comprising of components (A) and (B) exhibit synergistic herbicidal effects, where (A) is one or more herbicides selected from the group consisting of heteroaryloxy- and aryloxy-phenoxypropionic acids, their salts and esters and cyclohexanediones, and (B) is one or more herbicides selected from the group consisting of (B1) herbicides which are selective in rice, mainly against monocotyledonous plants, (B2) herbicides which are selective in rice, mainly against dicotyledonous harmful plants and cyperaceae, (B3) herbicides which are selective in rice, mainly against cyperaceae and (B4) herbicides which are selective in rice, mainly against monocotyledonous and dicotyledonous plants and cyperaceae.

Abstract: The 15?,16?-methylene-17-hydroxy-19-nor-17-pregna-4-en-3-one-21-carboxylic acid ?-lactone derivatives of the present invention possess progestational efficacy. They have the general chemical formula I, in which Z is selected from the group comprising an oxygen atom, two hydrogen atoms, NOR and NNHSO2R, where R is hydrogen, C1-C10-alkyl, aryl or C7-C20-aralkyl, R4 is hydrogen or halogen, and moreover either: R6a, R6b together form methylene or 1,2-ethanediyl or R6a is hydrogen and R6b is selected from the group comprising hydrogen, C1-C10-alkyl, C2-C10-alkenyl or C2-C10-alkynyl, and R7 is selected from the group comprising hydrogen, C1-C10-alkyl, C3-C6-cycloalkyl, C2-C10-alkenyl or C2-C10-alkynyl, or: R6a is hydrogen and R6b and R7, together, denote a bond, an oxygen or form methylene, R18 represents hydrogen or C1-C3-alkyl and in addition include their solvates, hydrates, stereoisomers and salts.

Abstract: The present invention relates to polycarbonate compositions having improved processing stability, increased heat stability and a good natural colour, and to their preparation and use, wherein the polycarbonate compositions contain an adsorber or absorber and an acid. The present invention relates further to a compounding process for the preparation of heat stabilised polycarbonate compositions containing constituents having a basic action, using acids applied to an adsorber or absorber. The present invention relates further to the use of Brönsted acids applied to an adsorber or absorber for the heat stabilisation of polymer mixtures, containing basic impurities, containing at least one polymer prepared by polycondensation, during compounding and thermal shaping.

Abstract: The present invention relates to thermoplastic polyurethane moulding compositions with improved surface resistance (write resistance and scratch resistance) and very good technical processibility and also to the use thereof.

Abstract: Methods for the reductive post-treatment of NaCl-containing solutions, wherein such methods comprise: providing a NaCl-containing solution obtained from an anode side of an NaCl electrolysis cell, the solution comprising reducible components; and subjecting the solution to cathodic electrochemical reduction.

Abstract: The present invention relates to a process for the preparation of low-viscosity polyisocyanate reaction products which contain allophanate groups, can be readily emulsified in water and contain activated groups which react, by polymerization, with ethylenically unsaturated compounds under the action of actinic radiation. The present invention furthermore relates to the products which can be prepared by the process according to the invention and their use.

Abstract: The present application relates to new binder-drug conjugates (ADCs) of N,N-dialkylauristatins that are directed against the target C4.4a, to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for treating and/or preventing illnesses, and also to the use of these ADCs for producing medicaments for treating and/or preventing illnesses, more particularly hyperproliferative and/or angiogenic diseases such as, for example, cancer diseases. Such treatments may be practised as a monotherapy or else in combination with other medicaments or further therapeutic measures.

Abstract: The present invention relates to a process for the preparation of highly reactive, low-viscosity and water-dilutable polyisocyanate reaction products which contain activated groups which react, by polymerization, with ethylenically unsaturated compounds under the action of actinic radiation. The present invention furthermore relates to a process for the preparation of such products and their use.

Abstract: The present invention relates to a process for the preparation of highly reactive, low-viscosity and water-dilutable polyisocyanate reaction products which contain activated groups which react, by polymerization, with ethylenically unsaturated compounds under the action of actinic radiation. The present invention furthermore relates to a process for the preparation of such products and their use.

Abstract: Herbicide combinations (A)+(8), if appropriate in the presence of safeners, with an effective content of (A) broad-spectrum herbicides from the group (A 1) glufosinate (salts) and related compounds (A2) glyphosate (salts) and related compounds such as sulfosate, (A3) imidazolinones such as imazethapyr, imazapyr, imazaquin, imazamox or their salts and (A4) herbicidal azoles from the group of the protoporphyrinogen oxidase inhibitors (PPO inhibitors) and (A5) the hydroxybenzonitriles and (B) herbicides from the group consisting of (B0) one or more structurally different herbicides from the abovementioned group (A), (B1) foliar- and soil-acting herbicides which are effective against monocotyledonous and dicotyledonous harmful plants, (B2) predominantly foliar-acting herbicides which are effective against dicotyledonous harmful plants, (B3) predominantly foliar-acting herbicides which are effective against monocotyledonous harmful plants, and (B4) foliar- and soil-acting herbicides which are effective agai

Abstract: The present invention relates to flame resistant moulding compositions comprising polycarbonates and graft polymers which, in addition to good flow properties, exhibit good (notched) impact strength and high chemical resistance with a UL94V-0 classification at 1.5 mm. These moulding compositions are particularly suitable for thin-walled housing parts in the electrical and electronics sector.

Abstract: The invention relates to a method for producing medicaments that contain vardenafil hydrochloride, essentially as trihydrate in solid form, and to medicaments that can be obtained according to this method