Patents by Inventor Beat Albert Imhof

Beat Albert Imhof has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vascular adhesion molecules and modulation of their function
    Patent number: 8143056
    Abstract: The invention relates to new polypeptides in isolated form belonging to a subfamily of the human immunoglobulin superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3, upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: March 27, 2012
    Assignee: Merck Serono SA
    Inventors: Beat Albert Imhof, Michel Aurrand-Lions
  • Junctional adhesion molecule-C (JAM-C) binding compounds and methods of their use
    Patent number: 8007797
    Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: August 30, 2011
    Assignee: Merck Serono S.A.
    Inventors: Pierre-Yves Dietrich, Mirna Tenan, Michel Aurrand-Lions, Beat Albert Imhof
  • VASCULAR ADHESION MOLECULES AND MODULATION OF THEIR FUNCTION
    Publication number: 20100267649
    Abstract: The invention relates to new polypeptides in isolated form belonging to a subfamily of the human immunoglobulin superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3, upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
    Type: Application
    Filed: February 10, 2010
    Publication date: October 21, 2010
    Inventors: Beat Albert Imhof, Michel Aurrand-Lions
  • Confluence regulated adhesion molecules useful in modulating vascular permeability
    Patent number: 7670826
    Abstract: The invention relates to new polypeptides in isolated form belonging to a subfamily of the human immunoglobulin superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3, upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: March 2, 2010
    Assignee: Merck Serono SA
    Inventors: Beat Albert Imhof, Michel Aurrand-Lions
  • JUNCTIONAL ADHESION MOLECULE-C (JAM-C) BINDING COMPOUNDS AND METHODS OF THEIR USE
    Publication number: 20100034737
    Abstract: The present invention relates to the use of a compound that specifically binds to JAM-C or JAM-B for the treatment of gliomas. More specifically the invention relates to the use of an antagonist of JAM-B or JAM-C for the treatment of glioma, in particular astrocytoma.
    Type: Application
    Filed: September 28, 2007
    Publication date: February 11, 2010
    Inventors: Pierre-Yves Dietrich, Mirna Tenan, Michel Aurrand-lions, Beat Albert Imhof
  • VASCULAR ADHESION MOLECULES AND MODULATION OF THEIR FUNCTION
    Publication number: 20080274970
    Abstract: The invention relates to new polypeptides in isolated form belonging to a subfamily of the human immunoglobulin superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3, upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
    Type: Application
    Filed: June 12, 2008
    Publication date: November 6, 2008
    Inventors: Beat Albert Imhof, Michel Aurrand-Lions
  • Confluence regulated adhesion molecules useful in modulating vascular permeability
    Patent number: 7393651
    Abstract: The invention relates to new polypeptide in isolated form belonging to a subfamily of the human Immunoglobulin Superfamily, which polypeptide shows at least 70% sequence homology with the amino acid sequence of the murine Confluency Regulated Adhesion Molecules 1 or 2 (CRAM-1 or CRAM-2) as depicted in FIG. 3 upper and second row, respectively, and antibodies thereto as well as their use in treatment of inflammation and tumors.
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: July 1, 2008
    Assignee: Laboratoires Serono S.A.
    Inventors: Beat Albert Imhof, Michel Aurrand-Lions