Patents by Inventor Beate Aue

Beate Aue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of macimorelin in assessing growth hormone deficiency in children
    Patent number: 11644474
    Abstract: The present invention provides a method for measuring growth hormone level in a human child, including a method of assessing pituitary-related growth hormone deficiency in a human child as a stand-alone test. The method includes the steps of oral administration of an effective amount of macimorelin to the child, collecting from the child two or three post-administration blood samples within a range of about 60 minutes after administration, and determining the level of growth hormone in the samples. The method can be used for diagnosing pituitary-related growth hormone deficiency in a child when the peak level of determined growth hormone in the samples is below a cut-off value.
    Type: Grant
    Filed: July 14, 2021
    Date of Patent: May 9, 2023
    Assignee: ÆTERNA ZENTARIS GMBH
    Inventors: Nicola Ammer, Michael Teifel, Beate Aue
  • USE OF MACIMORELIN IN ASSESSING GROWTH HORMONE DEFICIENCY IN CHILDREN
    Publication number: 20220026449
    Abstract: The present invention relates to a method for measuring growth hormone level in a human child, including a method of assessing pituitary-related growth hormone deficiency in a human child as a stand-alone test. The method comprises oral administration of an effective amount of macimorelin to the child, collecting from the child two or up to four post-administration blood samples within a range of about 90 minutes after administration, and determining the level of growth hormone in the samples. The method can be used for diagnosing pituitary-related growth hormone deficiency in a child when the peak level of determined growth hormone in the samples is below a cut-off value.
    Type: Application
    Filed: July 14, 2021
    Publication date: January 27, 2022
    Inventors: Nicola Ammer, Michael Teifel, Beate Aue
  • Indole derivatives and their use as medicament
    Patent number: 8008324
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: August 30, 2011
    Assignee: AEterna Zentaris GmbH
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Gunther
  • Indole derivatives and their use as medicament
    Patent number: 7989453
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: August 2, 2011
    Assignee: AEterna Zentaris GmbH
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Gunther
  • Novel indole derivatives and their use as medicament
    Publication number: 20080153875
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: March 6, 2008
    Publication date: June 26, 2008
    Applicant: AEterna Zentaris GmbH
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Gunther
  • Novel indole derivatives and their use as medicament
    Publication number: 20080108819
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: December 20, 2007
    Publication date: May 8, 2008
    Applicant: AEterna Zentaris GmbH
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Gunther
  • Indole derivatives and their use as medicaments
    Patent number: 7365081
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: April 29, 2008
    Assignee: AEterna Zentaris GmbH
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Günther
  • New anthracene derivatives and their use as pharmaceutical preparations
    Publication number: 20040110756
    Abstract: The invention relates to new anthracene derivatives of the general Formula 1 and to their synthesis and use as pharmaceutical preparations, especially for the treatment of a tumor.
    Type: Application
    Filed: July 17, 2003
    Publication date: June 10, 2004
    Inventors: Peter Emig, Eckhard Gunther, Beate Aue, Emmanuel Polymeropoulos, Silke Baasner, Peter Schmidt
  • Heteroaryl derivatives and their use as medicaments
    Patent number: 6706722
    Abstract: The invention relates to novel acridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: March 16, 2004
    Assignee: Zentaris AG
    Inventors: Peter Emig, Eckhard Günther, Bernd Nickel, Gerhard Bacher, Silke Baasner, Thomas Beckers, Beate Aue
  • Novel indole derivatives and their use as medicaments
    Publication number: 20030100597
    Abstract: The invention relates to novel indole derivatives of the general formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: July 20, 2001
    Publication date: May 29, 2003
    Inventors: Peter Emig, Gerald Bacher, Dietmar Reichert, Silke Basner, Beate Aue, Bernd Nickel, Eckhard Gnther
  • Novel heteroaryl derivatives and their use as medicaments
    Publication number: 20020132821
    Abstract: The invention relates to novel acridine derivatives of formula 1, to their preparation and to their use as medicaments, in particular for treating tumors.
    Type: Application
    Filed: July 20, 2001
    Publication date: September 19, 2002
    Inventors: Peter Emig, Eckhard Gnther, Bernd Nickel, Gerald Bacher, Silke Baasner, Thomas Beckers, Beate Aue