Patents by Inventor Beate SABLE

Beate SABLE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING DLL3-EXPRESSING CANCER
    Publication number: 20260201027
    Abstract: The disclosure provides methods for treating small cell lung cancer (SCLC) in a subject expressing human delta-like ligand 3 (DLL3) protein. The methods comprise administering to the subject an antigen-binding molecule comprising at least a first binding domain that binds to human DLL3, wherein at least 25% of the SCLC cells express DLL3, or wherein at least 25% of the SCLC cells express DLL3 at an intensity equal to or greater than 2+ as determined by an IHC assay.
    Type: Application
    Filed: December 7, 2023
    Publication date: July 16, 2026
    Applicant: AMGEN INC.
    Inventors: Nooshin HASHEMI SADRAEI, Mukul MINOCHA, Amanda GOLDRICK, Xi CHEN, Mira KISTLER, Chia-Hsin JU, Aaron ELLISON, Amrita PATI, Beate SABLE
  • Biomarkers and use of MET inhibitor for treatment of cancer
    Patent number: 10328062
    Abstract: The present invention relates to methods of therapeutic treatment of cancer using selective tyrosine kinase inhibitors and cancer biomarkers, such as MET amplification and high Met expression for patient selection.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: June 25, 2019
    Assignee: Amgen, Inc.
    Inventors: Sean Caenepeel, Angela Coxon, Zhiqiang Du, Paul Hughes, Robert Loberg, Gataree Ngarmchamnanrith, Beate Sable
  • BIOMARKERS AND USE OF MET INHIBITOR FOR TREATMENT OF CANCER
    Publication number: 20170182016
    Abstract: The present invention relates to methods of therapeutic treatment of cancer using selective tyrosine kinase inhibitors and cancer biomarkers, such as MET amplification and high Met expression for patient selection.
    Type: Application
    Filed: April 3, 2015
    Publication date: June 29, 2017
    Inventors: Sean CAENEPEEL, Angela COXON, Zhiqiang DU, Paul HUGHES, Robert LOBERG, Gift NGARMCHAMNANRITH, Beate SABLE