Patents by Inventor Beatrice Cameron

Beatrice Cameron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020187527
    Abstract: The invention discloses the preparation of DNA, in particular plasmid DNA. More particularly it concerns the production of bacterial plasmid DNA to be used in gene therapy, in the form of plasmid, minicircle supercoiled, loose or linear.
    Type: Application
    Filed: December 28, 2001
    Publication date: December 12, 2002
    Inventors: Joel Crouzet, Beatrice Cameron
  • Patent number: 6492164
    Abstract: Double-stranded DNA molecules characterized in that they are circular and in that they essentially include one or more genes of interest.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: December 10, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Joël Crouzet, Daniel Scherman, Béatrice Cameron, Pierre Wils, Anne-Marie Darquet
  • Publication number: 20020102247
    Abstract: The present invention relates to a nucleic acid sequence characterized in that it is derived from the wild nucleic acid sequence coding for a thymidine kinase, said nucleic acid sequence having at least one mutation in the region corresponding to the ATP binding site and conveniently a second mutation in the N-terminal region and/or C-terminal region. It also relates to variants of the wild thymidine kinase and their use in genic therapy.
    Type: Application
    Filed: December 12, 2000
    Publication date: August 1, 2002
    Inventors: Joel Crouzet, Francis Blanche, Michel Couder, Beatrice Cameron
  • Patent number: 6410273
    Abstract: The invention discloses the preparation of DNA, in particular plasmid DNA. More particularly it concerns the production of bacterial plasmid DNA to be used in gene therapy, in the form of plasmid, minicircle supercoiled, loose or linear.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: June 25, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Joël Crouzet, Béatrice Cameron
  • Publication number: 20020037565
    Abstract: The invention concerns a novel method for purifying and quantifying viral particles. More particularly, the invention concerns a method for purifying and quantifying adenovirus by ion-exchange chromatography. The invention also concerns a method for identifying different adenovirus serotypes.
    Type: Application
    Filed: June 14, 2001
    Publication date: March 28, 2002
    Inventors: Francis Blanche, Anne Barbot, Beatrice Cameron
  • Patent number: 6319672
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: November 20, 2001
    Assignee: Aventis Pharma S.A.
    Inventors: Joël Crouzet, Daniel Scherman, Pierre Wils, Françis Blanche, Béatrice Cameron
  • Patent number: 6207150
    Abstract: The present invention relates to a nucleic acid sequence characterized in that it is derived from the wild nucleic acid sequence coding for a thymidine kinase, said nucleic acid sequence having at least one mutation in the region corresponding to the ATP binding site and conveniently a second mutation in the N-terminal region and/or C-terminal region. It also relates to variants of the wild thymidine kinase and their use in genic therapy.
    Type: Grant
    Filed: August 6, 1998
    Date of Patent: March 27, 2001
    Assignee: Aventis Pharma S.A.
    Inventors: Joël Crouzet, Francis Blanche, Michel Couder, Béatrice Cameron
  • Patent number: 6156545
    Abstract: The present invention relates to a biosynthetic process for preparing cobalamines. More precisely, it relates to a process for amplifying the production of cobalamines and, more specifically, of coenzyme B.sub.12 by means of recombinant DNA techniques and/or by means of adding a novel cobalamine precursor.
    Type: Grant
    Filed: March 2, 1999
    Date of Patent: December 5, 2000
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Laurent Debussche, Denis Thibaut, Elisabeth Remy
  • Patent number: 6153597
    Abstract: A pharmaceutical composition useful for nucleic acid transfection is disclosed. The composition contains, in addition to a nucleic acid and at least one transfection agent, at least one compound that combines DNA binding properties with a nuclear DNA vectorisation capability, and preferably belongs to the HMG ("High mobility group") protein family. The use of said composition for in vitro, ex vivo and/or in vivo nucleic acid transfer is also disclosed.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: November 28, 2000
    Assignee: Aventis Pharma S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Vincent Thuillier
  • Patent number: 6143530
    Abstract: Double-stranded DNA molecules characterised in that they are circular and in that they essentially include one or more genes of interest.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: November 7, 2000
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Joel Crouzet, Daniel Scherman, Beatrice Cameron, Pierre Wils, Anne-Marie Darquet
  • Patent number: 6143518
    Abstract: Expression plasmids comprising a nucleic acid sequence of interest controlled by a T7 bacteriophage promoter and a stabilizing region comprising all or part of the par region of the RP4 plasmid or a derivative thereof. The invention also concerns the use of said plasmids in the production of recombinant products.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: November 7, 2000
    Assignee: Rhone-Poulenc Rorer SA
    Inventors: Beatrice Cameron, Joel Crouzet
  • Patent number: 6001631
    Abstract: A novel topoisomerase IV, nucleotide sequences coding for said enzyme, corresponding vectors, and the use of said enzyme for screening biologically active materials.
    Type: Grant
    Filed: January 24, 1997
    Date of Patent: December 14, 1999
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Francis Blanche, Beatrice Cameron, Joel Crouzet, Alain Famechon, Lucia Ferrero
  • Patent number: 5691163
    Abstract: Cells with an alteration at least in the gene involved in betaine catabolism, their preparation and their use, in particular for producing metabolites and/or enzymes, are disclosed.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: November 25, 1997
    Assignee: Rhone-Poulenc Rorer SA
    Inventors: Beatrice Cameron, Joel Crouzet
  • Patent number: 5670343
    Abstract: The present invention relates to new cloning and/or expression vectors having a broad host range in Gram-negative bacteria, in particular, in the production of recombinant proteins or of metabolites, or in bioconversion reactions, as well as to the host cells containing such vectors.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: September 23, 1997
    Assignee: Rhone Poulenc Biochimie
    Inventors: Beatrice Cameron, Joel Crouzet, Sophie Levy-Schil