Patents by Inventor Beatrice Maria Arico

Beatrice Maria Arico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Adjuvanted combinations of meningococcal factor H binding proteins
    Patent number: 10596246
    Abstract: The M01573 sequence of meningococcal fHbp offers poor coverage in a vaccine. The invention addresses this poor coverage in two ways. In a first aspect, a fHbp-based vaccine includes two family I fHbp sequences, one which is more closely related to MC58 than to M01573, and vice versa. In a second aspect, a multi-family fHbp-based vaccine uses a family I fHbp sequence which is more closely related to MC58 than to M01573, in combination with a family III fHbp sequence. The compositions are adjuvanted with an aluminium phosphate adjuvant.
    Type: Grant
    Filed: December 29, 2011
    Date of Patent: March 24, 2020
    Assignee: GLAXOSMITHKLINE BIOLOGICAL SA
    Inventors: Beatrice Maria Arico, Brunella Brunelli, Maurizio Comanducci, Mariagrazia Pizza, Silvana Savino, Maria Scarselli
  • Polypeptides from non-typeable
    Patent number: 9102729
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: August 11, 2015
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventors: Vega Masignani, Beatrice Maria Arico
  • ADJUVANTED COMBINATIONS OF MENINGOCOCCAL FACTOR H BINDING PROTEINS
    Publication number: 20150209419
    Abstract: The M01573 sequence of meningococcal fHbp offers poor coverage in a vaccine. The invention addresses this poor coverage in two ways. In a first aspect, a fHbp-based vaccine includes two family I fHbp sequences, one which is more closely related to MC58 than to M01573, and vice versa. In a second aspect, a multi-family fHbp-based vaccine uses a family I fHbp sequence which is more closely related to MC58 than to M01573, in combination with a family III fHbp sequence. The compositions are adjuvanted with an aluminium phosphate adjuvant.
    Type: Application
    Filed: December 29, 2011
    Publication date: July 30, 2015
    Inventors: Beatrice Maria Arico, Brunella Brunelli, Maurizio Comanducci, Mariagrazia Pizza, Silvana Savino, Maria Scarselli
  • POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE
    Publication number: 20140234363
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be usedin medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Application
    Filed: April 29, 2014
    Publication date: August 21, 2014
    Applicant: Novartis Vaccines and Diagnostics SRL
    Inventors: Vega Masignani, Beatrice Maria Arico
  • POLYPEPTIDES FROM NON-TYPEABLE HAEMOPHILUS INFLUENZAE
    Publication number: 20120148615
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Application
    Filed: January 24, 2012
    Publication date: June 14, 2012
    Inventors: Vega MASIGNANI, Beatrice Maria Arico
  • Polypeptides from non-typeable
    Patent number: 8124098
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Grant
    Filed: May 25, 2010
    Date of Patent: February 28, 2012
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventors: Vega Masignani, Beatrice Maria Arico
  • Polypeptides from non-typeable haemophilus influenzae
    Publication number: 20100303822
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Application
    Filed: May 25, 2010
    Publication date: December 2, 2010
    Inventors: Vega Masignani, Beatrice Maria Aricò
  • Polypeptides from non-typeable
    Patent number: 7749518
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Grant
    Filed: May 16, 2005
    Date of Patent: July 6, 2010
    Assignee: Novartis Vaccines and Diagnostics SRL
    Inventors: Vega Masignani, Beatrice Maria Arico
  • Polypeptides from Non-Typeable Haemophilus Influenzae
    Publication number: 20080267966
    Abstract: Polypeptides comprising non-typeable Haemophilus influenzae (NTHi) amino acid sequences. Over 2500 specific NTHi proteins are disclosed. The invention also provides related polypeptides, nucleic acids, antibodies and methods. These can all be used in medicine for treating or preventing disease and/or infection caused by H. influenzae, such as otitis media.
    Type: Application
    Filed: May 16, 2005
    Publication date: October 30, 2008
    Inventors: Vega Masignani, Beatrice Maria Arico