Patents by Inventor Beatrice Ruhland

Beatrice Ruhland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antagonists of follicle stimulating hormone activity
    Patent number: 6426357
    Abstract: The present invention provides a compound of the formula: and methods for using the same, wherein R1, R2, R3, R4 and X are those defined herein.
    Type: Grant
    Filed: July 31, 2000
    Date of Patent: July 30, 2002
    Assignee: Affymax, Inc.
    Inventors: Randall A. Scheuerman, Stephen D. Yanofsky, Christopher P. Holmes, Derek MacLean, Beatrice Ruhland, Ronald W. Barrett, Jay E. Wrobel, Ariamala Gopalsamy
  • Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1
    Patent number: 5786322
    Abstract: Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 28, 1998
    Assignee: Affymax Technologies N.V.
    Inventors: Ronald W. Barrett, Steven E. Cwirla, William J. Dower, Kerry J. Koller, Jung Lee, Christine L. Martens, Beatrice Ruhland-Fritsch
  • Peptides and compounds that bind selectins including endothelium leukocyte adhesion molecule 1 (ELAM-1)
    Patent number: 5728802
    Abstract: Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: March 17, 1998
    Assignee: Affymax Technologies N.V.
    Inventors: Ronald W. Barrett, Steven E. Cwirla, William J. Dower, Kerry J. Koller, Jung Lee, Christine L. Martens, Beatrice Ruhland
  • Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
    Patent number: 5643873
    Abstract: Disclosed are peptides and peptide mimetics that bind selectins, including endothelial leukocyte adhesion molecule 1 (ELAM-1). Such peptides and peptide mimetics are useful in methods for blocking adhesion of leukocytes to the selectins for the purpose of inhibiting inflammation as well as in diagnostic methods employing labeled peptides and peptide mimetics that bind selectins for the purpose of determining the site of inflammation in mammals which inflammation is mediated by the presence of one or more selectins.
    Type: Grant
    Filed: May 11, 1994
    Date of Patent: July 1, 1997
    Assignee: Affymax Technologies N.V.
    Inventors: Ronald W. Barrett, Steven E. Cwirla, William J. Dower, Kerry J. Koller, Jung Lee, Christine L. Martens, Beatrice Ruhland-Fritsch
  • Acyclic purine phosphonate nucleotide analogs as antiviral agents, and related synthetic methods
    Patent number: 5532225
    Abstract: Acyclic purine phosphonate nucleotide analogs useful to treat herpes viral infections are provided in enantiomerically pure form. These antiviral agents have the structural formula (Ia) or (Ib) ##STR1## and may be in acid, salt or ester form. Such compounds may also be dehydrated to provide antiviral agents in cyclic form. Pharmaceutical compositions are provided containing the antiviral agents, as is a chiral synthesis which may be used to prepare the agents in enantiomerically pure form or as a racemic mixture.
    Type: Grant
    Filed: July 31, 1992
    Date of Patent: July 2, 1996
    Assignee: SRI International
    Inventors: Elmer J. Reist, Beatrice Ruhland-Fritsch, Pricilla A. Sturm
  • Compounds having GABA like activity, and use of same in tissue irrigating solutions
    Patent number: 4952573
    Abstract: Compounds which enhance the efficiency of the corneal endothelial fluid pump thereby promoting normal corneal function and deturgescence of swollen corneas, and methods for the compounds' synthesis are described. In addition, surgical irrigating solutions which include one or more of the compounds are discussed along with methods for their use.
    Type: Grant
    Filed: March 23, 1988
    Date of Patent: August 28, 1990
    Assignee: Laboratoirs Alcon S.A.
    Inventors: Gerard LeClerc, Beatrice Ruhland, Guy Andermann, Georges de Burlet, Michel Dietz