Patents by Inventor Beatrice WAGNER

Beatrice WAGNER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HALOALKYL FUCOSE-CONTAINING SELECTIN ANTAGONISTS
    Publication number: 20200316100
    Abstract: Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin to an E-selectin ligand are disclosed. For example, haloalkyl fucose-containing E-selectin antagonists and compositions comprising at least one such agent are described.
    Type: Application
    Filed: May 22, 2017
    Publication date: October 8, 2020
    Applicant: GycoMimetics, Inc.
    Inventors: Beat ERNST, Norbert VARGA, Martin SMIESKO, Beatrice WAGNER, John M. PETERSON, John L. MAGNANI
  • Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker
    Publication number: 20200171005
    Abstract: Compounds, compositions, and methods for modulating in vitro and in vivo processes mediated by selectin binding. For example, heterobifunctional compounds that inhibit both E-selectins and P-selectins are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids). The compounds are of formula (Ia) wherein the substituents are as defined in the claims.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 4, 2020
    Applicant: GlycoMimetics, Inc.
    Inventors: Beat ERNST, Beatrice WAGNER
  • Heterobifunctional Pan-Selectin Antagonists Having a Triazole Linker
    Publication number: 20180369205
    Abstract: Compounds, compositions, and methods for modulating in vitro and in vivo processes mediated by selectin binding. For example, heterobifunctional compounds that inhibit both E-selectins and P-selectins are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-mediated function comprise particular glycomimetics linked to a member of a class of compounds termed BASAs (Benzyl Amino Sulfonic Acids). The compounds are of formula (Ia) wherein the substituents are as defined in the claims.
    Type: Application
    Filed: November 30, 2016
    Publication date: December 27, 2018
    Applicant: GlycoMimetics, Inc.
    Inventors: Beat ERNST, Beatrice WAGNER