Patents by Inventor Beatrice WANG

Beatrice WANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY RECEPTOR IGM ANTIBODIES AND USES THEREOF
    Publication number: 20230203173
    Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
    Type: Application
    Filed: November 14, 2022
    Publication date: June 29, 2023
    Inventors: Beatrice WANG, Max Allen SCHWARZER, Bruce Alan KEYT, Ramesh BALIGA
  • USE OF A MULTIMERIC ANTI-DR5 BINDING MOLECULE IN COMBINATION WITH A CANCER THERAPY FOR TREATING CANCER
    Publication number: 20230174660
    Abstract: This disclosure provides therapeutic methods for treating cancer including combination therapy with a multimeric anti-DR5 antibody and a cancer therapy, e.g., radiation, an anthracycline, a folic acid analog, a platinum-based agent, a taxane, a topoisomerase II inhibitor, a SMAC mimetic, a vinca alkaloid, a Brutons tyrosine kinase (BTK) inhibitor, a phosphoinositide 3-kinase delta (PI3K?) inhibitor, a myeloid cell leukemia-1 (Mcl-1) inhibitor, or any combination thereof.
    Type: Application
    Filed: May 12, 2021
    Publication date: June 8, 2023
    Inventors: Beatrice WANG, Thomas J. MATTHEW, Eric William HUMKE, Angus SINCLAIR, Daniel S. CHEN, Bruce Alan KEYT, Ling WANG
  • Polynucleotides encoding death domain-containing receptor-5 (DR5) binding molecules
    Patent number: 11578131
    Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
    Type: Grant
    Filed: April 28, 2020
    Date of Patent: February 14, 2023
    Assignee: IGM Biosciences, Inc.
    Inventors: Beatrice Wang, Max Allen Schwarzer, Bruce Alan Keyt, Ramesh Baliga
  • TUMOR NECROSIS FACTOR (TNF) SUPERFAMILY RECEPTOR BINDING MOLECULES AND USES THEREOF
    Publication number: 20210047419
    Abstract: This disclosure provides dimeric, pentameric, and hexameric Tumor Necrosis Factor (TNF) superfamily receptor protein binding molecules and methods of using such binding molecules to direct apoptosis-mediated killing of TNF receptor-expressing cells.
    Type: Application
    Filed: April 28, 2020
    Publication date: February 18, 2021
    Inventors: Beatrice WANG, Max Allen SCHWARZER, Bruce Alan KEYT, Ramesh BALIGA