Patents by Inventor Beatris Flores

Beatris Flores has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapamycin 40-O-cyclic hydrocarbon esters, compositions and methods
    Patent number: 11383009
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: July 12, 2022
    Assignee: Biotronik AG
    Inventors: Ronald E. Betts, John Dang Nguyen, Beatris Flores
  • Rapamycin 40-O-Cyclic Hydrocarbon Esters, Compositions and Methods
    Publication number: 20200345902
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Inventors: Ronald E. Betts, John Dang Nguyen, Beatris Flores
  • Rapamycin 40-O-cyclic hydrocarbon esters, compositions and methods
    Patent number: 10751450
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: August 25, 2020
    Assignee: Biotronik AG
    Inventors: Ronald E. Betts, John Dang Nguyen, Beatris Flores
  • Rapamycin 40-O-Cyclic Hydrocarbon Esters, Compositions and Methods
    Publication number: 20190290810
    Abstract: A new class of rapamycin 40-O-cyclic hydrocarbon esters is disclosed. The 40-O position of the rapamycin ester has the form 40-O—R, where R is C(O)—(CH2)n—X, n is 0, 1 or 2, and X is a cyclic hydrocarbon having 3-8 carbons, optionally containing one or more unsaturated bonds, and one or more linear (CH2)n) and/or cyclic (X) carbon atoms may have an OH or halide group. Also disclosed are therapeutic compositions and methods that employ the novel analogs.
    Type: Application
    Filed: March 20, 2019
    Publication date: September 26, 2019
    Inventors: Ronald E. Betts, John Dang Nguyen, Beatris Flores