Patents by Inventor Beatrix Bahle

Beatrix Bahle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RT-qPCR analysis of micro-dissected material from stained FFPET section
    Patent number: 11155852
    Abstract: The present invention refers to a method for immuno-histochemical staining of a formalin-fixed, paraffin-embedded tissue section comprising the steps of a) providing a solid support, b) mounting the formalin-fixed, paraffin-embedded tissue section onto the solid support, c) removing the paraffin from the formalin-fixed, paraffin-embedded tissue section, d) heating the tissue section mounted on the solid support to retrieve epitopes at 50 to 70° C. for 12 to 24 h, and e) staining the tissue section mounted on the solid support, wherein at least step e) is performed in the presence of 0.5 to 3.0 M sodium chloride. The present invention further refers to a kit for performing the method.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: October 26, 2021
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Beatrix Bahle, Andrea Herold, Sabine Lohmann, Sabine Moosmann, Julian Schuster, Monika Singer
  • RT-qPCR Analysis of Micro-Dissected Material from Stained FFPET Section
    Publication number: 20180346964
    Abstract: The present invention refers to a method for immuno-histochemical staining of a formalin-fixed, paraffin-embedded tissue section comprising the steps of a) providing a solid support, b) mounting the formalin-fixed, paraffin-embedded tissue section onto the solid support, c) removing the paraffin from the formalin-fixed, paraffin-embedded tissue section, d) heating the tissue section mounted on the solid support to retrieve epitopes at 50 to 70° C. for 12 to 24 h, and e) staining the tissue section mounted on the solid support, wherein at least step e) is performed in the presence of 0.5 to 3.0 M sodium chloride. The present invention further refers to a kit for performing the method.
    Type: Application
    Filed: July 23, 2018
    Publication date: December 6, 2018
    Inventors: Beatrix Bahle, Andrea Herold, Sabine Lohmann, Sabine Moosmann, Julian Schuster, Monika Singer
  • RT-qPCR analysis of micro-dissected material from stained FFPET section
    Patent number: 10059980
    Abstract: The present invention refers to a method for immuno-histochemical staining of a formalin-fixed, paraffin-embedded tissue section comprising the steps of a) providing a solid support, b) mounting the formalin-fixed, paraffin-embedded tissue section onto the solid support, c) removing the paraffin from the formalin-fixed, paraffin-embedded tissue section, d) heating the tissue section mounted on the solid support to retrieve epitopes at 50 to 70° C. for 12 to 24 h, and e) staining the tissue section mounted on the solid support, wherein at least step e) is performed in the presence of 0.5 to 3.0 M sodium chloride. The present invention further refers to a kit for performing the method.
    Type: Grant
    Filed: January 22, 2014
    Date of Patent: August 28, 2018
    Assignee: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Beatrix Bahle, Andrea Herold, Sabine Lohmann, Sabine Moosmann, Julian Schuster, Monika Singer
  • RT-qPCR analysis of micro-dissected material from stained FFPET section
    Publication number: 20150353992
    Abstract: The present invention refers to a method for immuno-histochemical staining of a formalin-fixed, paraffin-embedded tissue section comprising the steps of a) providing a solid support, b) mounting the formalin-fixed, paraffin-embedded tissue section onto the solid support, c) removing the paraffin from the formalin-fixed, paraffin-embedded tissue section, d) heating the tissue section mounted on the solid support to retrieve epitopes at 50 to 70° C. for 12 to 24 h, and e) staining the tissue section mounted on the solid support, wherein at least step e) is performed in the presence of 0.5 to 3.0 M sodium chloride. The present invention further refers to a kit for performing the method.
    Type: Application
    Filed: January 22, 2014
    Publication date: December 10, 2015
    Inventors: Beatrix Bahle, Andrea Herold, Sabine Lohmann, Sabine Moosmann, Julian Schuster, Monika Singer