Patents by Inventor Beau Peelle

Beau Peelle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions comprising GFP
    Patent number: 7528242
    Abstract: The invention relates to methods and compositions utilizing Renilla green fluorescent proteins (rGFP), and Ptilosarcus green fluorescent proteins (pGFP). In particular, the invention relates to the use of Renilla GFP or Ptilosarcus GFP proteins as reporters for cell assays, particularly intracellular assays, including methods of screening libraries using rGFP or pGFP.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: May 5, 2009
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: David Anderson, Beau Peelle
  • Multifunctional biomaterials as scaffolds for electronic, optical, magnetic, semiconducting, and biotechnological applications
    Patent number: 7488593
    Abstract: One-dimensional ring structures form M13 viruses were constructed by two genetic modifications encoding binding peptides and synthesis of a heterobifunctional linker molecule. The bifunctional viruses displayed an anti-streptavidin peptide and hexahistidine (SEQ ID NO: 4) peptide at opposite ends of the virus as pIII and pIX fusions. Stoichiometic addition of the streptavidin-NiNTA linker molecule led to the reversible formation of virus-based nanorings with circumferences corresponding to lengths of the packagable DNAs. These virus-based ring structures can be further engineered to nucleate inorganic materials and form metallic, magnetic, or semiconductor nanorings using trifunctionalized viruses.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: February 10, 2009
    Assignees: Board of Regents, The University of Texas System, Massachusetts Institute of Technology
    Inventors: Angela M. Belcher, Beau Peelle, Ki Tae Nam
  • Methods and compositions comprising Renilla GFP
    Publication number: 20070298973
    Abstract: The invention relates to methods and compositions utilizing Renilla green fluorescent proteins (rGFP), and Ptilosarcus green fluorescent proteins (pGFP). In particular, the invention relates to the use of Renilla GFP or Ptilosarcus GFP proteins as reporters for cell assays, particularly intracellular assays, including methods of screening libraries using rGFP or pGFP.
    Type: Application
    Filed: July 8, 2005
    Publication date: December 27, 2007
    Inventors: David Anderson, Beau Peelle
  • Discosoma red fluorescent proteins
    Patent number: 7193052
    Abstract: The present invention relates to directed protein evolution in mammalian cells and improved mutants of Discosoma sp. red fluorescent proteins.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: March 20, 2007
    Assignees: Rigel Pharmaceuticals, Incorporated, Becton, Dickinson and Company
    Inventor: Beau Peelle
  • Methods and compositions comprising GFP
    Patent number: 7090976
    Abstract: The invention relates to methods and compositions utilizing Renilla green fluorescent proteins (rGFP), and Ptilosarcus green fluorescent proteins (pGFP). In particular, the invention relates to the use of Renilla GFP or Ptilosarcus GFP proteins as reporters for cell assays, particularly intracellular assays, including methods of screening libraries using rGFP or pGFP.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: August 15, 2006
    Assignee: Rigel Pharmaceuticals, Inc.
    Inventors: David Anderson, Beau Peelle
  • Cell display libraries
    Publication number: 20060003387
    Abstract: Eukaryotic cell display libraries for use in panning processes comprising expressed biomolecules for specific and selective binding and enrichment to solid material surfaces including, for example, metal, magnetic, and semiconducting surfaces. Display can be regulated. Peptide and protein display on yeast cells are preferred. Solid materials can be fabricated in the presence of cell display libraries which have been subjected to panning against the solid materials. Nanoparticles can be grown in the presence of the biomolecules from reactive precursors. The nanoparticles can show quantum confinement effects. Self-healing films can be prepared.
    Type: Application
    Filed: February 7, 2005
    Publication date: January 5, 2006
    Inventors: Beau Peelle, Angela Belcher, Karl Wittrup, Eric Krauland
  • Multifunctional biomaterials as scaffolds for electronic, optical, magnetic, semiconducting, and biotechnological applications
    Publication number: 20050170336
    Abstract: One-dimensional ring structures form M13 viruses were constructed by two genetic modifications encoding binding peptides and synthesis of a heterobifunctional linker molecule. The bifunctional viruses displayed an anti-streptavidin peptide and hexahistidine (SEO ID NO: 4) peptide at opposite ends of the virus as pIII and pIX fusions. Stoichiometic addition of the streptavidin-NiNTA linker molecule led to the reversible formation of virus-based nanorings with circumferences corresponding to lengths of the packagable DNAs. These virus-based ring structures can be further engineered to nucleate inorganic materials and form metallic, magnetic, or semiconductor nanorings using trifunctionalized viruses.
    Type: Application
    Filed: October 15, 2004
    Publication date: August 4, 2005
    Inventors: Angela Belcher, Beau Peelle, Ki Nam
  • Directed evolution of protein in Mammalian cells
    Publication number: 20040126850
    Abstract: The present invention relates to directed protein evolution in mammalian cells and improved mutants of Discosoma sp. red fluorescent proteins.
    Type: Application
    Filed: December 17, 2003
    Publication date: July 1, 2004
    Applicants: Rigel Pharmaceuticals, Incorporated, Becton, Dickinson and Company
    Inventor: Beau Peelle
  • Directed evolution of protein in mammalian cells
    Patent number: 6723537
    Abstract: The present invention relates to directed protein evolution in mammalian cells and improved mutants of Discosoma sp. red fluorescent proteins.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: April 20, 2004
    Assignees: Rigel Pharmaceuticals, Incorporated, Becton, Dickinson and Company
    Inventor: Beau Peelle
  • Methods and compositions comprising Renilla GFP
    Publication number: 20030149254
    Abstract: The invention relates to methods and compositions utilizing Renilla green fluorescent proteins (rGFP), and Ptilosarcus green fluorescent proteins (pGFP). In particular, the invention relates to the use of Renilla GFP or Ptilosarcus GFP proteins as reporters for cell assays, particularly intracellular assays, including methods of screening libraries using rGFP or pGFP.
    Type: Application
    Filed: April 24, 2002
    Publication date: August 7, 2003
    Applicant: Rigel Pharmaceuticals, Inc.
    Inventors: David Anderson, Beau Peelle
  • Directed evolution of protein in mammalian cells
    Publication number: 20030077730
    Abstract: The present invention relates to directed protein evolution in mammalian cells and improved mutants of Discosoma sp. red fluorescent proteins.
    Type: Application
    Filed: May 20, 2002
    Publication date: April 24, 2003
    Applicant: Rigel Pharmaceuticals, Incorporated
    Inventor: Beau Peelle