Patents by Inventor Beau R. Webber

Beau R. Webber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCING EFFICIENCY OF TARGETED GENE KNOCKIN BY BASE EDITORS
    Publication number: 20240101993
    Abstract: The present invention provides genomic engineering methods that utilize base editors to perform targeted gene knockins and gene knockouts with high efficiency. Cells that have been genetically modified according to these methods are also provided, as are methods of using the modified cells in a treatment for cancer.
    Type: Application
    Filed: January 21, 2022
    Publication date: March 28, 2024
    Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Beau R. Webber, Branden S. Moriarity, Walker Lahr, Nicholas Slipek, Mitchell G. Kluesner
  • METHODS, COMPOSITIONS, AND KITS FOR EXPANDING NATURAL KILLER CELLS
    Publication number: 20230399618
    Abstract: Provided herein are methods, compositions, and kits for expanding natural killer cells in the absence of feeder cells.
    Type: Application
    Filed: November 10, 2022
    Publication date: December 14, 2023
    Applicant: Regents of the University of Minnesota
    Inventors: Branden Scott Moriarity, Jae Woong Chang, Beau R. Webber
  • Method for correcting a genetic sequence
    Patent number: 10648002
    Abstract: Methods of gene correction, methods of generating induced pluripotent stem cells (iPSCs), and methods of deriving multi-lineage cell types with therapeutic value. In some embodiments, the gene correction affects the expression and/or function of the functional type VII collagen protein (C7).
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: May 12, 2020
    Assignee: REGENTS OF THE UNIVERSITY OF MINNESOTA
    Inventors: Beau R. Webber, Mark J. Osborn, Jakub Tolar, Bruce R. Blazar
  • HUMAN T CELL DERIVED FROM T CELL-DERIVED INDUCED PLURIPOTENT STEM CELL AND METHODS OF MAKING AND USING
    Publication number: 20180362927
    Abstract: Induced pluripotent stem cells (iPSCs) derived from a T cell of a T cell subset. T cells derived from iPSCs derived from a T cell. Methods of deriving iPSCs from a T cell. Methods of deriving T cells from iPSCs including deriving a T cell of a T cell subset from an iPSC. Methods of engineering chimeric antigen receptor (CAR)-expressing or T cell receptor (TCR)-expressing iPSC. Methods of administering T cells derived using the methods disclosed. Induced pluripotent stem cell lines derived from T cells, methods of deriving induced pluripotent stem cell lines, and methods of deriving T cells from induced pluripotent stem cell lines.
    Type: Application
    Filed: December 8, 2016
    Publication date: December 20, 2018
    Inventors: Bruce R. BLAZAR, Dharmeshkumar PATEL, Beau R. WEBBER, Jakub TOLAR
  • METHOD FOR CORRECTING A GENETIC SEQUENCE
    Publication number: 20180142262
    Abstract: Methods of gene correction, methods of generating induced pluripotent stem cells (iPSCs), and methods of deriving multi-lineage cell types with therapeutic value. In some embodiments, the gene correction affects the expression and/or function of the functional type VII collagen protein (C7).
    Type: Application
    Filed: November 22, 2017
    Publication date: May 24, 2018
    Inventors: Beau R. Webber, Mark J. Osborn, Jakub Tolar, Bruce R. Blazar