Abstract: The present invention relates generally to a vascular access device having a septum positioned within a lumen of the device, the device further having a pusher for providing a fluid pathway through the septum. In particular, the present invention relates to systems and methods for improving flow of a fluid through the access device, while minimizing stagnation of fluids within the device. These systems and methods include various modified fluid pathways and interactions between the vascular access device body, the septum and the pusher.

Abstract: Syringe assemblies having a passive disabling system to prevent reuse are provided. According to one or more embodiments, the syringe assembly comprises a barrel, plunger rod and stopper wherein the plunger rod further comprises a flexible protrusion that locks the plunger rod within the barrel. Certain embodiments further include a frangible portion on the plunger rod that breaks when reuse is attempted.

Abstract: A device for priming and venting a hazardous drug within an intravenous administration set. The device includes various access ports and fluid channels to permit direct injection of a hazardous drug into the fluid reservoir, while eliminating the possibility of undesirable exposure to the hazardous drug. The device further includes priming and flushing ports to enable flushing of a hazardous drug from the system following an infusion procedure.

Abstract: The present invention provides polymeric film and, more particularly, a multi-layer polymeric film including one or more structural layers of homogenous polypropylene; one or more structural layers of random copolymer polypropylene; one or more anhydride modified polyethylene based tie layers; one or more linear low density polyethylene (LLDPE) blend sealant layers having a primary LLDPE component, a secondary LLDPE component, and an optional LDPE additive component

Abstract: The present invention provides polymeric film and, more particularly, a multi-layer polymeric film including one or more structural layers of homogenous polypropylene; one or more structural layers of random copolymer polypropylene; one or more anhydride modified polyethylene based tie layers; one or more linear low density polyethylene (LLDPE) blend sealant layers having a primary LLDPE component, a secondary LLDPE component, and an optional LDPE additive component.

Abstract: A catheter assembly is disclosed, which includes a catheter adapter. A port is disposed in the catheter adapter to provide selective access to the interior of the catheter adapter, and can be used for fluid flushing or infusion. A valve is disposed within the catheter adapter that includes a one-way valve portion that prevents proximally-directed fluid flow. The valve further including a flexible tube portion that covers an opening between the port and the catheter adapter.

Abstract: Methods of the invention include the isolation of intact, viable microorganism(s) from positive blood culture (“PBC”) samples for use in downstream analyses such as identification and antimicrobial susceptibility testing (“AST”). The methods involve collecting a portion of the PBC sample, adding a choline-containing solution, lysing the blood cells, isolating the viable microorganism, and performing downstream analysis of the isolated, viable microorganism. The methods can be applied to a variety of gram-positive bacteria, gram-negative bacteria, and/or yeast, and particularly to strains of S. pneumoniae.