Patents by Inventor Bede PORTZ

Bede PORTZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEIC ACIDS AND NUCLEIC ACID ANALOGS FOR TREATING, PREVENTING, AND DISRUPTING PATHOLOGICAL POLYNUCLEOTIDE-BINDING PROTEIN INCLUSIONS
    Publication number: 20210169914
    Abstract: Disclosed herein are methods to treat a neurodegenerative disease comprising administering to a subject with a neurodegenerative disease a therapeutically effective amount of a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease. Also disclosed are methods to inhibit protein aggregation in a cell comprising contacting the cell with a composition comprising a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease. Additionally disclosed are compositions comprising a polynucleotide that binds a nucleic acid-binding polypeptide, wherein the nucleic acid-binding polypeptide can aggregate in cells and is associated with a neurodegenerative disease.
    Type: Application
    Filed: August 16, 2019
    Publication date: June 10, 2021
    Inventors: Christopher DONNELLY, Jacob MANN, James SHORTER, Lin GUO, Bede PORTZ