Patents by Inventor Been-Ren Lin

Been-Ren Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR MODULATING INVASION ABILITY OF A TUMOR AND METHODS THEREOF
    Publication number: 20150258173
    Abstract: The present invention provides a composition for modulating invasion ability of a tumor, comprising: an effective amount of an activator for a miRNA-mediated pathway or an effective amount of a modulating member in the miRNA-mediated pathway being a modulating member, and wherein the miRNA-mediated pathway is regulated by at least one miRNA selected from the group consisting of miR-346, miR-504 and miR-1179. The composition functions according to a novel model that an activator or a modulating member can regulate cellular invasion/migration of tumor via a miRNA-mediated pathway, and thereby can be a potential candidate of molecular drug to treat the tumor by modulating its invasion ability. A method for treating or preventing tumor invasion method is provided as well. Meanwhile, a method for detecting the invasive ability of a tumor in a subject and the kit thereof are also provided.
    Type: Application
    Filed: June 2, 2015
    Publication date: September 17, 2015
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Cheng-Chi CHANG, Been-Ren LIN, Yen-Ping KUO
  • Methods for inhibiting peritoneal dissemination of cancer cells
    Patent number: 8871721
    Abstract: A pharmaceutical composition for treating or preventing peritoneal dissemination is provided. The pharmaceutical composition includes an effective dose of connective tissue growth factor (CTGF) and a pharmaceutically acceptable carrier thereof.
    Type: Grant
    Filed: March 1, 2012
    Date of Patent: October 28, 2014
    Inventors: Min-Liang Kuo, Been-Ren Lin, Cheng-Chi Chang, Chiung-Nine Chen
  • COMPOSITIONS FOR MODULATING INVASION ABILITY OF A TUMOR AND METHODS THEREOF
    Publication number: 20140073686
    Abstract: The present invention provides a composition for modulating invasion ability of a tumor, comprising: an effective amount of an activator for a miRNA-mediated pathway or an effective amount of a modulating member in the miRNA-mediated pathway being a modulating member, and wherein the miRNA-mediated pathway is regulated by at least one miRNA selected from the group consisting of miR-346, miR-504 and miR-1179. The composition functions according to a novel model that an activator or a modulating member can regulate cellular invasion/migration of tumor via a miRNA-mediated pathway, and thereby can be a potential candidate of molecular drug to treat the tumor by modulating its invasion ability. A method for treating or preventing tumor invasion method is provided as well. Meanwhile, a method for detecting the invasive ability of a tumor in a subject and the kit thereof are also provided.
    Type: Application
    Filed: September 13, 2012
    Publication date: March 13, 2014
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: Cheng-Chi CHANG, Been-Ren LIN, Yen-Ping KUO
  • PHARMACEUTICAL COMPOSITION FOR INHIBITING PERITONEAL DISSEMINATION
    Publication number: 20120165253
    Abstract: A pharmaceutical composition for treating or preventing peritoneal dissemination is provided. The pharmaceutical composition includes an effective dose of connective tissue growth factor (CTGF) and an acceptable receptor thereof.
    Type: Application
    Filed: March 1, 2012
    Publication date: June 28, 2012
    Inventors: Min-Liang KUO, Been-Ren Lin, Cheng-Chi Chang, Chiung-Nine Chen
  • Pharmaceutical composition for inhibiting peritoneal dissemination
    Publication number: 20100331249
    Abstract: A pharmaceutical composition for treating or preventing peritoneal dissemination is provided. The pharmaceutical composition includes an effective dose of connective tissue growth factor (CTGF) and an acceptable receptor thereof.
    Type: Application
    Filed: July 23, 2008
    Publication date: December 30, 2010
    Inventors: Min-Liang Kuo, Been-Ren Lin, Cheng-Chi Chang, Chiung-Nine Chen