Patents by Inventor Beena Bhatia

Beena Bhatia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 9-Aminomethyl Substituted Minocycline Compounds
    Publication number: 20100113400
    Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: May 28, 2009
    Publication date: May 6, 2010
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Mohamed Y. Ismail, Laura Honeyman, Todd Bowser, Beena Bhatia
  • 7,9-substituted tetracycline compounds
    Patent number: 7696186
    Abstract: The present invention pertains to novel 7,9-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: April 13, 2010
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Y. Ismail, Todd Bowser, Laura McIntyre, Beena Bhatia, Paul Hawkins, Laxma Reddy, Karen Stapleton, Tadeusz Warchol, Paul Sheahan
  • 9-SUBSTITUTED MINOCYCLINE COMPOUNDS
    Publication number: 20090325908
    Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: January 9, 2009
    Publication date: December 31, 2009
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Y. Ismail, Todd Bowser, Jimmy Dumornay, Glen Rennie, Gui Liu, Darrell J. Koza, Paul Sheahan, Karen Stapleton, Paul Hawkins, Beena Bhatia, Atul K. Verma, Laura Honeyman, Tadeusz Warchol, David Messersmith
  • 7-SUBSTITUTED TETRACYCLINE COMPOUNDS
    Publication number: 20090306022
    Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 10, 2009
    Applicants: Trustees of Tufts College, Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Mohamed Ismail, Todd Bowser, Beena Bhatia, David Messersmith, Laura McIntyre, Darrell Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul Verma, Tadeusz Warchol, Upul Bandarage
  • 7-substituted tetracycline compounds
    Patent number: 7595309
    Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: May 24, 2004
    Date of Patent: September 29, 2009
    Assignees: Trustees of Tufts College, Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Beena Bhatia, David Messersmith, Mohamed Y. Ismail, Todd Bowser, Laura McIntyre, Darrell J. Koza, Glen Rennie, Paul Sheahan, Paul Hawkins, Atul K. Verma, Tadeusz Warchol, Upul Bandarage
  • 9-aminomethyl substituted minocycline compounds
    Patent number: 7553828
    Abstract: The present invention pertains, at least in part, to novel 9-substituted minocycline compounds. These minocycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and minocycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: June 30, 2009
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Roger Frechette, Mohamed Y. Ismail, Laura Honeyman, Todd Bowser, Beena Bhatia
  • Transcription factor modulating compounds and methods of use thereof
    Publication number: 20090131401
    Abstract: Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
    Type: Application
    Filed: February 12, 2008
    Publication date: May 21, 2009
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Stuart B. Levy, Michael N. Alekshun, Brent L. Podlogar, Kwasi Ohemeng, Atul K. Verma, Tadeusz Warchol, Beena Bhatia, Todd Bowser, Mark Grier
  • Substituted Tetracycline Compounds for Treatment of Inflammatory Skin Disorders
    Publication number: 20080312193
    Abstract: Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
    Type: Application
    Filed: December 21, 2007
    Publication date: December 18, 2008
    Inventors: Haregewein Assefa, Beena Bhatia, Michael Draper, Laura Honeyman, Oak K. Kim, Dennis P. Molnar
  • Transcription factor modulating compounds and methods of use thereof
    Patent number: 7405235
    Abstract: Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: July 29, 2008
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Stuart B. Levy, Michael N. Alekshun, Brent L. Podlogar, Kwasi Ohemeng, Atul K. Verma, Tadeusz Warchol, Beena Bhatia, Todd Bowser, Mark Grier
  • Amino-methyl substituted tetracycline compounds
    Patent number: 7326696
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Grant
    Filed: December 15, 2003
    Date of Patent: February 5, 2008
    Assignee: Paratek Pharmaceuticals, Inc.
    Inventors: Mark L. Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Y. Ismail, Oak Kim, Rachid Mechiche, N. Laxma Reddy, Atul K. Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov
  • Amino-methyl substituted tetracycline compounds
    Publication number: 20080015169
    Abstract: Aminomethyl substituted tetracycline compounds, pharmaceutical compositions, and methods of use thereof are discussed.
    Type: Application
    Filed: June 5, 2007
    Publication date: January 17, 2008
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Laura Honeyman, Mohamed Ismail, Oak Kim, Rachid Mechiche, N. Reddy, Atul Verma, Peter Viski, Tadeusz Warchol, Ivan Yanachkov
  • 13-Substituted methacycline compounds
    Publication number: 20070072834
    Abstract: 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
    Type: Application
    Filed: April 4, 2006
    Publication date: March 29, 2007
    Applicants: Paratek Pharmaceuticals, Inc., Trustees of Tufts College
    Inventors: Mark Nelson, Beena Bhatia, Laura McIntyre, Glen Rennie
  • Prodrugs of 9-aminomethyl tetracycline compounds
    Publication number: 20060287283
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: January 12, 2006
    Publication date: December 21, 2006
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Victor Amoo, Haregewein Assefa, Beena Bhatia, Joel Berniac, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak Kim, Rachid Mechiche, Kwasi Ohemeng, Jingwen Pan
  • Substituted tetracycline compounds
    Publication number: 20060166945
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: October 25, 2005
    Publication date: July 27, 2006
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Paul Abato, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Mark Nelson, Kwasi Ohemeng, Jingwen Pan
  • 4-Aminotetracyclines and methods of use thereof
    Publication number: 20060166944
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: October 25, 2005
    Publication date: July 27, 2006
    Inventors: Joel Berniac, Beena Bhatia, Mark Grier, Mark Nelson, Jingwen Pan
  • 13-Substituted methacycline compounds
    Publication number: 20050143353
    Abstract: 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
    Type: Application
    Filed: December 17, 2004
    Publication date: June 30, 2005
    Applicants: Paratek Pharmaceuticals, Inc., Trustees of Tufts College
    Inventors: Mark Nelson, Beena Bhatia, Laura McIntyre, Glen Rennie
  • Substituted tetracycline compounds
    Publication number: 20050143352
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for tetracycline compounds such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 30, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Paul Abato, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Mohamed Ismail, Oak Kim, Jude Mathews, Rachid Mechiche
  • Prodrugs of 9-aminomethyl tetracycline compounds
    Publication number: 20050137174
    Abstract: The invention pertains to prodrugs of 9-aminomethyl substituted tetracycline compounds, methods of using the compounds, and pharmaceutical compositions containing them.
    Type: Application
    Filed: June 25, 2004
    Publication date: June 23, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Kwasi Ohemeng, Victor Amoo, Haregewein Assefa, Joel Berniac, Beena Bhatia, Todd Bowser, Jackson Chen, Mark Grier, Laura Honeyman, Oak Kim, Rachid Mechiche, Jingwen Pan
  • Transcription factor modulating compounds and methods of use thereof
    Publication number: 20050124678
    Abstract: Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
    Type: Application
    Filed: November 3, 2003
    Publication date: June 9, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Stuart Levy, Michael Alekshun, Brent Podlogar, Kwasi Ohemeng, Atul Verma, Tadeusz Warchol, Beena Bhatia, Todd Bowser, Mark Grier
  • Substituted tetracycline compounds
    Publication number: 20050038002
    Abstract: The present invention pertains, at least in part, to novel substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Application
    Filed: December 18, 2003
    Publication date: February 17, 2005
    Applicant: Paratek Pharmaceuticals, Inc.
    Inventors: Mark Nelson, Kwasi Ohemeng, Roger Frechette, Paul Abato, Victor Amoo, Upul Bandarage, Joel Berniac, Beena Bhatia, Jackson Chen, Mohamed Ismail, Oak Kim, Laura Honeyman, Rachid Mechiche, Andre Pearson, Laxma Nagavelli, Paul Sheahan, Atul Verma, Peter Viski, Tadeusz Warchol