Abstract: Described herein are bifunctional peptides, compositions comprising A the same, and methods useful for treatment of dental caries that have been treated with silver diamine fluoride. Treatment with bifunctional peptides remineralizes the carious region to address undesirable tooth discoloration associated with silver diamine fluoride treatment.

Abstract: A portable computer that is configurable between a plurality of display modes including a laptop mode (in which the portable computer has a conventional laptop appearance) and an easel mode in which the base of the computer and its display component stand vertically forming an inverted “V.” The portable computer includes a hinge assembly that couples the display component to the base of the computer, and allows the display component to be rotated about an axis along an interface between the display component and the base to configure the portable computer between a closed position, the laptop mode and the easel mode.

Abstract: According to various embodiments of the disclosure, an electronic device may include: a first housing, a second housing rotatably coupled with the first housing and configured to rotate between a first position at which the second housing at least partially faces the first housing and a second position at which the second housing is unfolded at a specified angle from the first position, a hinge module including a hinge providing at least one folding axis and rotatably coupling the first housing and the second housing about the folding axis, and a hinge cover disposed between the first housing and the second housing and coupled to surround at least a part of the hinge module, and at least one part of the hinge cover may be configured to be located closer to the hinge module at the second position than at the first position.

Abstract: Radial-armed thin-film bilayers are designed and fabricated from a metal and an oxide to produce grippers that interact with the yarns or fibers of the fabric and form a mechanical tangle attachment to the fabric. MEMs devices attached to the grippers enable the MEMs devices to be adhered to a flexible and/or extensible fabric. Fabrics comprise conventional textile, smart textiles, functional fibers or other smart materials. The fabrics thus incorporate wearable sensors, medical devices, and other functional MEMs for commercial, biomedical, industrial and scientific applications.

Abstract: A convolutional neural network (CNN) accelerator, including: a CNN circuit for performing a multiple-layer CNN computation, wherein the multiple layers are to receive an input feature according to an input feature map (IFM) and a weight matrix per output feature, wherein an output of a first layer provides an input for a next layer; and a mapping circuit to access a three-dimensional input matrix stored as a Z-major matrix; wherein the CNN circuit is to perform an inner-product direct convolution on the Z-major matrix, wherein the direct convolution lacks a lowering operation.

Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of retinal capillary non-perfusion. In particular, the present invention relates to a method of treating retinal capillary non-perfusion in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a ROCK inhibitor.

Abstract: In an example, an apparatus comprises a plurality of execution units comprising and logic, at least partially including hardware logic, to receive a plurality of data inputs for training a neural network, wherein the data inputs comprise training data and weights inputs; represent the data inputs in a first form; and represent the weight inputs in a second form. Other embodiments are also disclosed and claimed.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to configure heterogenous components in an accelerator. An example apparatus includes a graph compiler to identify a workload node in a workload and generate a selector for the workload node, and the selector to identify an input condition and an output condition of a compute building block, wherein the graph compiler is to, in response to obtaining the identified input condition and output condition from the selector, map the workload node to the compute building block.

Abstract: Methods and pharmaceutical compositions for the treatment of choroidal neovascularisation are provided. In particular, a method of treating choroidal neovascularisation in a subject in need thereof comprising administering to the subject a therapeutically effective amount of a mineralocorticoid receptor antagonist is provided.

Abstract: The present invention relates to novel piperazine derivatives, methods for their preparation, pharmaceutical compositions including such compounds, and methods of using these compounds and compositions, especially for targeted therapy treatment of hyperproliferative disorders, including benign hyperproliferative disorders, cancer and pre-cancer conditions.

Abstract: Embodiments described herein provide a processing apparatus comprising compute circuitry to generate neural network data for a convolutional neural network (CNN) and write the neural network data to a memory buffer. The compute circuitry additionally includes a direct memory access (DMA) controller including a hardware codec having encode circuitry and a decode circuitry. The DMA controller reads the neural network data from the memory buffer, encode the neural network data via the encode circuit, writes encoded neural network data to a memory device coupled with the processing apparatus, writes metadata for the encoded neural network data to the memory device coupled with the processing apparatus, and decodes encoded neural network data via the decode circuit in response to a request from the compute circuitry.

Abstract: Ocular Rosacea (OR) is a chronic inflammatory and neurovascular diseases of the ocular surface and eyelids. associated with abnormal tear film lipids that can lead to corneal neovascularization, loss of transparency and ulceration. Here, the inventors show that the combination of mineralocorticoid receptor blockade in association with local ocular glucocorticoids that have high GR binding affinity, have superior effects as compared to MR blockade alone, without the side effects of glucocorticoids on corneal wound healing. The combination of MR antagonist and low dose of a GR activator further reduces corneal edema, corneal neovascularization and improves corneal wound healing. The combination of MR antagonist and triamcinolone that has a strong GR binding affinity reinforces the beneficial effects of MR antagonists.

Abstract: A convolutional neural network (CNN) accelerator, including: a CNN circuit for performing a multiple-layer CNN computation, wherein the multiple layers are to receive an input feature according to an input feature map (IFM) and a weight matrix per output feature, wherein an output of a first layer provides an input for a next layer; and a mapping circuit to access a three-dimensional input matrix stored as a Z-major matrix; wherein the CNN circuit is to perform an inner-product direct convolution on the Z-major matrix, wherein the direct convolution lacks a lowering operation.

Abstract: This invention relates to the treatment of macular edema. Macular edema is the main cause of vision loss during diabetic macular edema, wet AMD (Age Related Macular Degeneration), retinal vein occlusion and chronic intraocular inflammation. Currently, beyond photocoagulation by laser irradiation, two types of drugs are used, protein molecules that neutralize VEGF family members and glucocorticoids, with different mechanisms of action, but targeting one single symptom: macular edema. The inventors have now found that macular edema may be treated by increasing the oncotic pressure of the vitreous. According to the inventors' understanding, causing an increase in the oncotic pressure of the vitreous induces a liquid flow from the interstitial water accumulated in the retina tissue to the vitreous compartment, so as to reduce or stop macular edema.

Abstract: The present invention provides methods of use of hexokinase 2 (HK2)/mitochondria-detaching compounds, including jasmonate derivatives and piperazine derivatives and pharmaceutical compositions including such compounds for inducing immune responses in a subject, including potentiating the immune response to hyperproliferative disorders such as cancer and potentiating the immune response to infectious diseases.

Abstract: A portable computer that is configurable between a plurality of display modes including a laptop mode (in which the portable computer has a conventional laptop appearance) and an easel mode in which the base of the computer and its display component stand vertically forming an inverted “V.” The portable computer includes a hinge assembly that couples the display component to the base of the computer, and allows the display component to be rotated about an axis along an interface between the display component and the base to configure the portable computer between a closed position, the laptop mode and the easel mode.

Abstract: A portable computer that is configurable between a plurality of display modes including a laptop mode (in which the portable computer has a conventional laptop appearance) and an easel mode in which the base of the computer and its display component stand vertically forming an inverted “V.” The portable computer includes a hinge assembly that couples the display component to the base of the computer, and allows the display component to be rotated about an axis along an interface between the display component and the base to configure the portable computer between a closed position, the laptop mode and the easel mode.