Patents by Inventor Behram Sethna

Behram Sethna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF
    Publication number: 20250084119
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Application
    Filed: March 19, 2024
    Publication date: March 13, 2025
    Inventors: John Henry BOUGHER, III, Ramamurty V S CHANGALVALA, Aaron Leigh DOWNEY, John C. DRACH, Ernest Randall LANIER, JR., Andrew Louis MCIVER, Bradley David ROBERTSON, Dean Wallace SELLESETH, Phiroze Behram SETHNA, Leroy TOWNSEND, Roy W. WARE
  • USES AND METHODS FOR RECURRENT PRIMARY CNS NEOPLASMS
    Publication number: 20240238297
    Abstract: This disclosure relates, at least in part, to a method of treatment. In one embodiment, the method of treatment comprises administering to a subject in need of such treatment at least a first therapeutic agent including ONC-206, 7-benzyl-4-(2,4-difluorobenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, for the treatment of one or more CNS neoplasms.
    Type: Application
    Filed: May 13, 2022
    Publication date: July 18, 2024
    Inventors: Joshua Edward Allen, Jill Christine CHAPPELL, Andrew Kang-Kang LEE, Odin Johann NADERER, Varun Vijay PRABHU, Phiroze Behram SETHNA
  • PYRROLOPYRIMIDINE NUCLEOSIDES FOR TREATING OR PREVENTING A SARS-COV-2 INFECTION
    Publication number: 20240207299
    Abstract: The present disclosure provides methods of treating or preventing a SARS-CoV-2 infection or a SARS-CoV-2-infection associated disease or disorder (e.g. COVID-19) comprising administering to a subject in need thereof an effective amount of a pyrrolopyrimidine nucleoside analog of the Formula I, Formula IA, Formula IB or Formula II and pharmaceutical compositions thereof wherein Rc and A are defined herein.
    Type: Application
    Filed: March 29, 2022
    Publication date: June 27, 2024
    Applicant: Chimerix, Inc.
    Inventors: Heidi Muth COLTON, Mohammed Anowrul KABIR, Ernest Randall LANIER, Jr., Phiroze Behram SETHNA, Roy W. WARE
  • Pyrrolopyrimidine nucleosides and analogs thereof
    Patent number: 11981700
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Grant
    Filed: January 27, 2021
    Date of Patent: May 14, 2024
    Assignees: Chimerix, Inc., The Regents of the University of Michigan
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, Aaron Leigh Downey, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF
    Publication number: 20220002335
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Application
    Filed: January 27, 2021
    Publication date: January 6, 2022
    Inventors: John Henry BOUGHER, III, Ramamurty V S CHANGALVALA, Aaron Leigh DOWNEY, John C. DRACH, Ernest Randall LANIER, JR., Andrew Louis MCIVER, Bradley David ROBERTSON, Dean Wallace SELLESETH, Phiroze Behram SETHNA, Leroy TOWNSEND, Roy W. WARE
  • Pyrrolopyrimidine nucleosides and analogs thereof
    Patent number: 10941175
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: March 9, 2021
    Assignees: Chimerix, Inc., The Regents of the University of Michigan
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, Aaron Leigh Downey, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF
    Publication number: 20200199167
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Application
    Filed: August 6, 2019
    Publication date: June 25, 2020
    Inventors: John Henry BOUGHER, III, Ramamurty V S CHANGALVALA, Aaron Leigh DOWNEY, John C. DRACH, Ernest Randall LANIER, Jr., Andrew Louis MCIVER, Bradley David ROBERTSON, Dean Wallace SELLESETH, Phiroze Behram SETHNA, Leroy TOWNSEND, Roy W. WARE
  • Pyrrolopyrimidine nucleosides and analogs thereof
    Patent number: 10407457
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: September 10, 2019
    Assignees: Chimerix, Inc., The Regents of the University of Michigan
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • PYRROLOPYRIMIDINE NUCLEOSIDES AND ANALOGS THEREOF
    Publication number: 20170253628
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Application
    Filed: May 18, 2017
    Publication date: September 7, 2017
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, Aaron Leigh Downey, John C. Drach, Ernest Randall Lanier, JR., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • Pyrrolopyrimidine nucleosides and analogs thereof
    Patent number: 9708359
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Grant
    Filed: August 8, 2016
    Date of Patent: July 18, 2017
    Assignees: Chimerix, Inc., The Regents of the University of Michigan
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, Aaron Leigh Downey, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • Pyrrolopyrimidine nucleosides and analogs thereof
    Patent number: 9701706
    Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: July 11, 2017
    Assignees: Chimerix, Inc., The Regents of the University of Michigan
    Inventors: John Henry Bougher, III, Ramamurty V S Changalvala, John C. Drach, Ernest Randall Lanier, Jr., Andrew Louis McIver, Bradley David Robertson, Dean Wallace Selleseth, Phiroze Behram Sethna, Leroy Townsend, Roy W. Ware
  • System and method for classification of moving object during video surveillance
    Patent number: 9082042
    Abstract: A system for classifying moving objects during video-based surveillance comprising: capturing a silhouette image of a moving object, resizing the captured image, computing an average height to width ratio and a center of gravity for the object in the resized image, dividing the resized image, comparing the average height to average width of the object and further comparing the variance of center of gravity with a predetermined threshold value to classify the object in the captured silhouette into predetermined classes.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: July 14, 2015
    Assignees: TATA CONSULTANCY SERVICES, ANNA UNIVERSITY
    Inventors: Behram Sethna, Mala John, Prasath Palaniappan, Sumithra Ganapathi
  • System and Method for Classification of Moving Object During Video Surveillance
    Publication number: 20120026328
    Abstract: A system for classifying moving objects during video-based surveillance comprising: capturing a silhouette image of a moving object, resizing the captured image, computing an average height to width ratio and a center of gravity for the object in the resized image, dividing the resized image, comparing the average height to average width of the object and further comparing the variance of center of gravity with a predetermined threshold value to classify the object in the captured silhouette into predetermined classes.
    Type: Application
    Filed: July 29, 2011
    Publication date: February 2, 2012
    Applicants: TATA CONSULTANCY SERVICES LIMITED, ANNA UNIVERSITY
    Inventors: Behram Sethna, Mala John, Prasath Palaniappan, Sumithra Ganapathi