Patents by Inventor Bei Chen

Bei Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPUTER-BASED EXTRACTION OF COMPLEX BUILDING OPERATION RULES FOR PRODUCTS AND SERVICES
    Publication number: 20150134585
    Abstract: A method for generating an operational rule associated with a building management system includes identifying, with a processing device, a first pattern associated with a series of operational observations corresponding to a property of the building management system, correlating a first contextual attribute with the first pattern, and deriving the operational rule at least in part based on the first pattern and the first contextual attribute.
    Type: Application
    Filed: November 13, 2013
    Publication date: May 14, 2015
    Applicant: International Business Machines Corporation
    Inventors: Bei Chen, Joern Ploennigs, Anika Schumann, Mathieu Sinn
  • COMPUTER-BASED EXTRACTION OF COMPLEX BUILDING OPERATION RULES FOR PRODUCTS AND SERVICES
    Publication number: 20150134586
    Abstract: A method for generating an operational rule associated with a building management system includes identifying, with a processing device, a first pattern associated with a series of operational observations corresponding to a property of the building management system, correlating a first contextual attribute with the first pattern, and deriving the operational rule at least in part based on the first pattern and the first contextual attribute.
    Type: Application
    Filed: December 16, 2013
    Publication date: May 14, 2015
    Applicant: International Business Machines Corporation
    Inventors: Bei Chen, Joern Ploennigs, Anika Schumann, Mathieu Sinn
  • COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
    Publication number: 20150105390
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Application
    Filed: December 17, 2014
    Publication date: April 16, 2015
    Applicant: IRM LLC, a Delaware Limited Liability Company
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, III, Wenshuo Lu, Bei Chen, Tetsuo Uno, Yunho Jin, Tao Jiang
  • Compounds and compositions as protein kinase inhibitors
    Patent number: 8957081
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Grant
    Filed: September 11, 2012
    Date of Patent: February 17, 2015
    Assignee: IRM LLC
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, III, Bei Chen, Tetsuo Uno, Yunho Jin, Tao Jiang
  • Compounds and compositions as kinase inhibitors
    Patent number: 8859574
    Abstract: The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or analplastic lymphoma kinase (ALK).
    Type: Grant
    Filed: July 23, 2013
    Date of Patent: October 14, 2014
    Assignee: IRM LLC
    Inventors: Thomas H. Marsilje, Wenshuo Lu, Bei Chen, Xiaohui He, Christian Cho-Hua Lee, Songchun Jiang, Kunyong Yang
  • Tablet Dosage Forms
    Publication number: 20140234415
    Abstract: The present invention features tablet dosage forms comprising two or more different active ingredients. In one embodiment, a tablet dosage form of the invention comprises a first layer and a second layer, wherein the first layer comprises polymer-based solid dispersion particles having a mean particle size of no more than 200 ?m.
    Type: Application
    Filed: February 19, 2014
    Publication date: August 21, 2014
    Inventors: Todd S. McDermott, Peter T. Mayer, Benjamin M. Collman, Weili Wang, Bei Chen
  • FLUOROPHENYL BICYCLIC HETEROARYL COMPOUNDS
    Publication number: 20130338152
    Abstract: The present invention provides a compound the invention, and its use as a IGF-1R inhibitor. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
    Type: Application
    Filed: March 8, 2012
    Publication date: December 19, 2013
    Applicants: IRM LLC, NOVARTIS AG
    Inventors: Bei Chen, Robin Alec Fairhurst, Songchun Jiang, Wenshuo Lu, Thomas H. Marsilje, III, Clive McCarthy, Pierre-Yves Michellys, Stefan Stutz
  • Compounds and compositions as protein kinase inhibitors
    Patent number: 8592432
    Abstract: The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: November 26, 2013
    Inventors: Bei Chen, Tao Jiang, Thomas H. Marsilje, Pierre-Yves Michellys, Truc Ngoc Nguyen, Wei Pei, Baogen Wu, Zhaobo Gao, Yonghui Ge, Chen Huang, Yuncheng Li, Xuefeng Zhu
  • COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
    Publication number: 20130310361
    Abstract: The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or analplastic lymphoma kinase (ALK).
    Type: Application
    Filed: July 23, 2013
    Publication date: November 21, 2013
    Inventors: Thomas H. Marsilje, Wenshuo Lu, Bei Chen, Xiaohui He, Christian Cho-Hua Lee, Songchun Jiang, Kunyong Yang
  • Pyrimidine derivatives as kinase inhibitors
    Patent number: 8519129
    Abstract: The invention provides novel pyrimidine derivatives of formula I and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-IR) or analplastic lymphoma kinase (ALK).
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: August 27, 2013
    Assignee: IRM LLC
    Inventors: Thomas H. Marsilje, III, Wenshuo Lu, Bei Chen, Xiaohui He, Christian Cho-Hua Lee, Songchun Jiang, Kunyong Yang
  • Pyrimidine derivatives as kinase inhibitors
    Patent number: 8445505
    Abstract: The invention provides novel pyrimidine derivatives of formula (I) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-IR) or analplastic lymphoma kinase (ALK).
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: May 21, 2013
    Assignee: IRM LLC
    Inventors: Thomas H. Marsilje, III, Wenshuo Lu, Bei Chen, Xiaohui He, Songchun Jiang, Kunyong Yang
  • 2-biphenylamino-4-aminopyrimidine derivatives as kinase inhibitors
    Patent number: 8440681
    Abstract: The invention provides novel pyrimidine derivatives of formula (1) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-1R) or anaplastic lymphoma kinase (ALK).
    Type: Grant
    Filed: August 27, 2008
    Date of Patent: May 14, 2013
    Assignee: IRM LLC
    Inventors: Thomas H. Marsilje, Wenshuo Lu, Bei Chen, Xiaohui He, Badry Bursulaya, Christian Cho-Hua Lee
  • Compounds and compositions as protein kinase inhibitors
    Patent number: 8399450
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: March 19, 2013
    Assignee: IRM LLC
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, Wenshuo Lu, Bei Chen, Tetsuo Uno, Yunho Jin, Tao Jiang
  • Compounds and compositions as protein kinase inhibitors
    Patent number: 8377921
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Grant
    Filed: June 29, 2011
    Date of Patent: February 19, 2013
    Assignee: IRM LLC
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, Bei Chen, Tetsuo Uno
  • Compounds and compositions as protein kinase inhibitors
    Patent number: 8372858
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Grant
    Filed: March 15, 2011
    Date of Patent: February 12, 2013
    Assignee: IRM LLC
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, Bei Chen, Tetsuo Uno, Yunho Jin, Tao Jiang
  • COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS
    Publication number: 20130005748
    Abstract: The invention provides novel pyrimidine and pyridine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine and pyridine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, focal adhesion kinase (FAK), zeta-chain-associated protein kinase 70 (ZAP-70), insulin-like growth factor (IGF-1R), or a combination thereof.
    Type: Application
    Filed: September 11, 2012
    Publication date: January 3, 2013
    Applicant: IRM LLC
    Inventors: Pierre-Yves Michellys, Wei Pei, Thomas H. Marsilje, Wenshuo Lu, Bei Chen, Tetsuo Uno, Yunho Jin, Tao Jiang
  • Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls
    Publication number: 20120289501
    Abstract: The invention relates to new derivatives of formula I, wherein the substituents are as defined in the specification; to processes for the preparation of such derivatives; pharmaceutical compositions comprising such derivatives; such derivatives as a medicament; such derivatives for the treatment of a proliferative disease.
    Type: Application
    Filed: November 23, 2010
    Publication date: November 15, 2012
    Applicant: NOVARTIS AG
    Inventors: Bei Chen, Robin Alec Fairhurst, Andreas Floersheimer, Pascal Furet, Songchun Jiang, Wenshuo Lu, Thomas H. Marsilje, III, Andrea Vaupel
  • Pen
    Patent number: D668292
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: October 2, 2012
    Assignee: Beifa Group Co., Ltd.
    Inventor: Bei Chen
  • Pen
    Patent number: D668293
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: October 2, 2012
    Assignee: Beifa Group Co., Ltd.
    Inventor: Bei Chen
  • Pen
    Patent number: D669127
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: October 16, 2012
    Assignee: Beifa Group Co., Ltd.
    Inventor: Bei Chen