Abstract: The present application provides an anti-CD38 antibody, an antigen-binding fragment thereof, and pharmaceutical use. Specifically, the present application provides a murine-derived antibody, a chimeric antibody or a humanized antibody comprising a CDR region of the anti-CD38 antibdoy, a pharmaceutical composition comprising the anti-CD38 antibody or the antigen-binding fragment thereof, and an application thereof as a drug. In particular, the present application provides an application of a humanized anti-CD38 antibody in preparing a drug for treating a CD38 positive disease or disorder.

Abstract: An elevator anti-fall buffer based on flexible guidance. The anti-fall buffer is used for connecting and fixing an end part of a braking steel rope of an elevator. The anti-fall buffer has an upper support plate and a lower support plate, wherein a pulley set is provided on the upper support plate and the lower support plate, and a hydraulic damping buffer is provided at two sides of the pulley set. The anti-fall buffer uses the energy consumption principle of a hydraulic damping hole, and while protecting the braking steel rope from the force of impact created thereon by the elevator, prevents the force of impact from a spring on the elevator post-braking, improving the safety and reliability of elevator braking, thereby improving safety of an elevator, while also using a pulley set can increase the braking distance of the braking steel rope, thereby lengthening life of the steel rope.

Abstract: An elevator anti-fall buffer based on flexible guidance. The anti-fall buffer is used for connecting and fixing an end part of a braking steel rope of an elevator. The anti-fall buffer has an upper support plate and a lower support plate, wherein a pulley set is provided on the upper support plate and the lower support plate, and a hydraulic damping buffer is provided at two sides of the pulley set. The anti-fall buffer uses the energy consumption principle of a hydraulic damping hole, and while protecting the braking steel rope from the force of impact created thereon by the elevator, prevents the force of impact from a spring on the elevator post-braking, improving the safety and reliability of elevator braking, thereby improving safety of an elevator, while also using a pulley set can increase the braking distance of the braking steel rope, thereby lengthening life of the steel rope.