Patents by Inventor Beibei Zhai

Beibei Zhai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF DIANHYDROGALACTITOL OR ANALOGS AND DERIVATIVES IN COMBINATION WITH A P53 MODULATOR OR A PARP INHIBITOR
    Publication number: 20200061054
    Abstract: Methods and compositions employing dianhydrogalactitol or a derivative analog of dianhydrogalactitol together with a p53 modulator, a PARP inhibitor, or topoisomerase inhibitor for treatment of malignancies are provided.
    Type: Application
    Filed: February 28, 2018
    Publication date: February 27, 2020
    Applicant: Del Mar Pharmaceuticals (BC) Ltd.
    Inventors: Jeffrey A. Bacha, Dennis M. Brown, Anne Steinø, Mads Daugaard, Beibei Zhai
  • USE OF DIANHYDROGALACTITOL AND DERIVATIVES THEREOF IN THE TREATMENT OF GLIOBLASTOMA, LUNG CANCER, AND OVARIAN CANCER
    Publication number: 20190091195
    Abstract: Substituted hexitol derivatives such as dianhydrogalactitol are useful in the treatment of various neoplastic pathologies. Said pathologies include glioblastoma multiforme, non-small-cell lung carcinoma (NSCLC), ovarian cancer, and leptomeningeal carcinomatosis. The anti-neoplastic activity of dianhydrogalactitol is demonstrated to be due to its activity as an alkylating agent that creates N7 methylation and inter-strand DNA crosslinks. The hexitol derivatives may be used alone or in combination with other anti-neoplastic agents.
    Type: Application
    Filed: September 9, 2016
    Publication date: March 28, 2019
    Applicant: Del Mar Pharmaceuticals
    Inventors: Jeffrey A. Bacha, Beibei Zhai, Anne Steinø, Mads Daugaard